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Immunosuppressive Myeloid Cells Induce Nitric Oxide-Dependent DNA Damage and p53 Pathway Activation in CD8+ T Cells.

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Bibliographic Details
Title: Immunosuppressive Myeloid Cells Induce Nitric Oxide-Dependent DNA Damage and p53 Pathway Activation in CD8+ T Cells.
Authors: Cartwright ANR; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Suo S; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Badrinath S; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Kumar S; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Melms J; Columbia Center for Translational Immunology, New York, New York.; Columbia University Medical Center, Division of Hematology and Oncology, New York, New York., Luoma A; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Bagati A; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Immunology, Harvard Medical School, Boston, Massachusetts., Saadatpour A; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Izar B; Columbia Center for Translational Immunology, New York, New York.; Columbia University Medical Center, Division of Hematology and Oncology, New York, New York., Yuan GC; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Wucherpfennig KW; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts. kai_wucherpfennig@dfci.harvard.edu.; Department of Immunology, Harvard Medical School, Boston, Massachusetts.; Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Source: Cancer immunology research [Cancer Immunol Res] 2021 Apr; Vol. 9 (4), pp. 470-485. Date of Electronic Publication: 2021 Jan 29.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2326-6074
DOI:10.1158/2326-6066.CIR-20-0085