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Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent β-l-Arabinofuranosidase Inhibitor.

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Title: Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent β-l-Arabinofuranosidase Inhibitor.
Authors: McGregor NGS; York Structural Biology Laboratory, Department of Chemistry, The University of York, Heslington, York, YO10 5DD, UK., Coines J; Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica) & Institut de Química Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Martí i Franquès 1, 08028, Barcelona, Spain., Borlandelli V; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300, RA, Leiden, The Netherlands., Amaki S; Department of Biotechnology, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8657, Japan., Artola M; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300, RA, Leiden, The Netherlands., Nin-Hill A; Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica) & Institut de Química Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Martí i Franquès 1, 08028, Barcelona, Spain., Linzel D; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300, RA, Leiden, The Netherlands., Yamada C; Department of Biotechnology, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8657, Japan., Arakawa T; Department of Biotechnology, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8657, Japan., Ishiwata A; Synthetic Cellular Chemistry Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan., Ito Y; Synthetic Cellular Chemistry Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.; Graduate School of Science, Osaka University, Toyonaka, Osaka, 560-0043, Japan., van der Marel GA; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300, RA, Leiden, The Netherlands., Codée JDC; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300, RA, Leiden, The Netherlands., Fushinobu S; Department of Biotechnology, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8657, Japan., Overkleeft HS; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300, RA, Leiden, The Netherlands., Rovira C; Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica) & Institut de Química Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Martí i Franquès 1, 08028, Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Passeig Lluís Companys 23, 08020, Barcelona, Spain., Davies GJ; York Structural Biology Laboratory, Department of Chemistry, The University of York, Heslington, York, YO10 5DD, UK.
Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Mar 08; Vol. 60 (11), pp. 5754-5758. Date of Electronic Publication: 2021 Feb 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22McGregor+NGS%22">McGregor NGS</searchLink>; York Structural Biology Laboratory, Department of Chemistry, The University of York, Heslington, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Coines+J%22">Coines J</searchLink>; Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica) & Institut de Química Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Martí i Franquès 1, 08028, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Borlandelli+V%22">Borlandelli V</searchLink>; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300, RA, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Amaki+S%22">Amaki S</searchLink>; Department of Biotechnology, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8657, Japan.<br /><searchLink fieldCode="AU" term="%22Artola+M%22">Artola M</searchLink>; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300, RA, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nin-Hill+A%22">Nin-Hill A</searchLink>; Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica) & Institut de Química Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Martí i Franquès 1, 08028, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Linzel+D%22">Linzel D</searchLink>; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300, RA, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Yamada+C%22">Yamada C</searchLink>; Department of Biotechnology, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8657, Japan.<br /><searchLink fieldCode="AU" term="%22Arakawa+T%22">Arakawa T</searchLink>; Department of Biotechnology, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8657, Japan.<br /><searchLink fieldCode="AU" term="%22Ishiwata+A%22">Ishiwata A</searchLink>; Synthetic Cellular Chemistry Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+Y%22">Ito Y</searchLink>; Synthetic Cellular Chemistry Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.; Graduate School of Science, Osaka University, Toyonaka, Osaka, 560-0043, Japan.<br /><searchLink fieldCode="AU" term="%22van+der+Marel+GA%22">van der Marel GA</searchLink>; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300, RA, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Codée+JDC%22">Codée JDC</searchLink>; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300, RA, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Fushinobu+S%22">Fushinobu S</searchLink>; Department of Biotechnology, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8657, Japan.<br /><searchLink fieldCode="AU" term="%22Overkleeft+HS%22">Overkleeft HS</searchLink>; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300, RA, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rovira+C%22">Rovira C</searchLink>; Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica) & Institut de Química Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Martí i Franquès 1, 08028, Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Passeig Lluís Companys 23, 08020, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Davies+GJ%22">Davies GJ</searchLink>; York Structural Biology Laboratory, Department of Chemistry, The University of York, Heslington, York, YO10 5DD, UK.
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