Development of an optimized and scalable method for isolation of umbilical cord blood-derived small extracellular vesicles for future clinical use.

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Title: Development of an optimized and scalable method for isolation of umbilical cord blood-derived small extracellular vesicles for future clinical use.
Authors: Cardoso RMS; Exogenus Therapeutics, S.A, Biocant Park, Cantanhede, Portugal., Rodrigues SC; Exogenus Therapeutics, S.A, Biocant Park, Cantanhede, Portugal.; Doctoral Programme in Experimental Biology and Biomedicine (PDBEB), Institute for Interdisciplinary Research (IIIUC), CNC-Center for Neuroscience and Cell Biology, University of Coimbra., Coimbra, Portugal., Gomes CF; Exogenus Therapeutics, S.A, Biocant Park, Cantanhede, Portugal., Duarte FV; Exogenus Therapeutics, S.A, Biocant Park, Cantanhede, Portugal., Romao M; Institut Curie, Paris Sciences Lettres Research University, Centre National de la Recherche Scientifique, UMR 144, Paris, France.; Cell and Tissue Imaging Core Facility PICT-IBiSA, Institut Curie, Paris, France., Leal EC; CNC-Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal.; 3Is-Institute for Interdisciplinary Research, University of Coimbra, Coimbra, Portugal., Freire PC; Exogenus Therapeutics, S.A, Biocant Park, Cantanhede, Portugal., Neves R; Exogenus Therapeutics, S.A, Biocant Park, Cantanhede, Portugal.; CNC-Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal.; 3Is-Institute for Interdisciplinary Research, University of Coimbra, Coimbra, Portugal., Simões-Correia J; Exogenus Therapeutics, S.A, Biocant Park, Cantanhede, Portugal.; CNC-Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal.
Source: Stem cells translational medicine [Stem Cells Transl Med] 2021 Jun; Vol. 10 (6), pp. 910-921. Date of Electronic Publication: 2021 Feb 12.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101578022 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2157-6580 (Electronic) Linking ISSN: 21576564 NLM ISO Abbreviation: Stem Cells Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2157-6580
DOI:10.1002/sctm.20-0376