Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction.

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Title: Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction.
Authors: Mainali R; Department of Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, United States., Zabalawi M; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, United States., Long D; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, United States., Buechler N; Department of Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, United States., Quillen E; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, United States., Key CC; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, United States., Zhu X; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, United States., Parks JS; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, United States., Furdui C; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, United States., Stacpoole PW; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine and Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, United States., Martinez J; Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Research Triangle Park, Bethesda, United States., McCall CE; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, United States., Quinn MA; Department of Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, United States.; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, United States.
Source: ELife [Elife] 2021 Feb 22; Vol. 10. Date of Electronic Publication: 2021 Feb 22.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2050-084X
DOI:10.7554/eLife.64611