Bromelain inhibits SARS-CoV-2 infection via targeting ACE-2, TMPRSS2, and spike protein.
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| Title: | Bromelain inhibits SARS-CoV-2 infection via targeting ACE-2, TMPRSS2, and spike protein. |
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| Authors: | Sagar S; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA., Rathinavel AK; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA., Lutz WE; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA., Struble LR; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA., Khurana S; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), FDA, Silver Spring, Maryland, USA., Schnaubelt AT; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA., Mishra NK; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, USA., Guda C; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA., Palermo NY; Computational Chemistry Core, University of Nebraska Medical Center, Omaha, Nebraska, USA., Broadhurst MJ; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA., Hoffmann T; Advanced Light and Electron Microscopy, Centre for Biological Threats and Special Pathogens 4 (ZBS 4), Robert Koch Institute, Berlin, Germany., Bayles KW; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA., Reid SPM; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA., Borgstahl GEO; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA., Radhakrishnan P; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA. |
| Source: | Clinical and translational medicine [Clin Transl Med] 2021 Feb; Vol. 11 (2), pp. e281. |
| Publication Type: | Letter |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Print ISSN: 2001-1326 (Print) Linking ISSN: 20011326 NLM ISO Abbreviation: Clin Transl Med |
| Database: | MEDLINE Ultimate |
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