Clinical response to dabrafenib plus trametinib in a pediatric ganglioglioma with BRAF p.T599dup mutation.

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Title: Clinical response to dabrafenib plus trametinib in a pediatric ganglioglioma with BRAF p.T599dup mutation.
Authors: Miller KE; The Steve and Cindy Rasmussen Institute for Genomic Medicine, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43215, USA., Schieffer KM; The Steve and Cindy Rasmussen Institute for Genomic Medicine, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43215, USA., Grischow O; The Steve and Cindy Rasmussen Institute for Genomic Medicine, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43215, USA., Rodriguez DP; Department of Radiology, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, Ohio 43210, USA., Cottrell CE; The Steve and Cindy Rasmussen Institute for Genomic Medicine, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43215, USA.; Department of Pathology, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA.; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA., Leonard JR; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA.; Department of Neurosurgery, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA.; Department of Neurosurgery, Nationwide Children's Hospital, Columbus, Ohio 43205, USA., Finlay JL; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA.; Division of Hematology/Oncology/Bone Marrow Transplantation, Nationwide Children's Hospital, Columbus, Ohio 43205, USA., Mardis ER; The Steve and Cindy Rasmussen Institute for Genomic Medicine, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43215, USA.; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA.; Department of Neurosurgery, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA.
Source: Cold Spring Harbor molecular case studies [Cold Spring Harb Mol Case Stud] 2021 Apr 08; Vol. 7 (2). Date of Electronic Publication: 2021 Apr 08 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 101660017 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2373-2873 (Electronic) Linking ISSN: 23732873 NLM ISO Abbreviation: Cold Spring Harb Mol Case Stud Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2373-2873
DOI:10.1101/mcs.a006023