Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial.

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Title: Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial.
Authors: Larson RA; Department of Medicine and Comprehensive Cancer Center, University of Chicago, Chicago, IL, USA. rlarson@medicine.bsd.uchicgo.edu., Mandrekar SJ; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.; Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN, USA., Huebner LJ; Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN, USA., Sanford BL; Alliance Statistics and Data Center, Duke University, Durham, NC, USA., Laumann K; Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN, USA., Geyer S; Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN, USA., Bloomfield CD; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Thiede C; Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden, Germany., Prior TW; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Döhner K; Department of Internal Medicine III, University of Ulm, Ulm, Germany., Marcucci G; City of Hope Comprehensive Cancer Center, Duarte, CA, USA., Voso MT; Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy., Klisovic RB; Emory University School of Medicine, Atlanta, GA, USA., Galinsky I; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Wei AH; Department of Clinical Haematology, The Alfred Hospital and Monash University, Melbourne, Australia., Sierra J; Hematology Department, Hospital de la Santa Creu i Sant Pau, IIB Sant Pau and Jose Carreras Leukemia Research Institute, Autonomous University of Barcelona, Barcelona, Spain., Sanz MA; Department of Hematology, Hospital Universitario y Politécnico La Fe and Department of Medicine, University of Valencia, Valencia, Spain., Brandwein JM; Department of Medicine, University of Alberta, Edmonton, AB, Canada., de Witte T; Radboud University Medical Centre, Nijmegen, Netherlands., Niederwieser D; Department of Hematology and Oncology, University of Leipzig, Leipzig, Germany., Appelbaum FR; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Medeiros BC; Division of Hematology, Stanford Comprehensive Cancer Center, Stanford University, Stanford, CA, USA., Tallman MS; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Krauter J; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany., Schlenk RF; Department of Internal Medicine III, University of Ulm, Ulm, Germany.; NCT Trial Center, National Center of Tumor Diseases, Heidelberg University Hospital and German Cancer Research Center, Heidelberg, Germany., Ganser A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany., Serve H; Department of Medicine II, Hematology/Oncology, Goethe University Hospital Frankfurt, Frankfurt/Main, Germany., Ehninger G; Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden, Germany., Amadori S; Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy., Gathmann I; Novartis Pharma AG, Basel, Switzerland., Döhner H; Department of Internal Medicine III, University of Ulm, Ulm, Germany., Stone RM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Source: Leukemia [Leukemia] 2021 Sep; Vol. 35 (9), pp. 2539-2551. Date of Electronic Publication: 2021 Mar 02.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5551
DOI:10.1038/s41375-021-01179-4