A Single Point Mutation, Asn16→Lys, Dictates the Temperature-Sensitivity of the Reovirus tsG453 Mutant.

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Title: A Single Point Mutation, Asn16→Lys, Dictates the Temperature-Sensitivity of the Reovirus tsG453 Mutant.
Authors: Glover KKM; Department of Medical Microbiology and Infectious Diseases, Room 543 Basic Medical Sciences Building, 745 Bannatyne Avenue, University of Manitoba, Winnipeg, MB R3E OJ9, Canada., Sutherland DM; Department of Pediatrics, University of Pittsburgh School of Medicine, 4401 Penn Avenue, Pittsburgh, PA 15224, USA.; Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue, Pittsburgh, PA 15224, USA., Dermody TS; Department of Pediatrics, University of Pittsburgh School of Medicine, 4401 Penn Avenue, Pittsburgh, PA 15224, USA.; Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue, Pittsburgh, PA 15224, USA.; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, 4401 Penn Avenue, Pittsburgh, PA 15224, USA., Coombs KM; Department of Medical Microbiology and Infectious Diseases, Room 543 Basic Medical Sciences Building, 745 Bannatyne Avenue, University of Manitoba, Winnipeg, MB R3E OJ9, Canada.; Manitoba Centre for Proteomics and Systems Biology, 715 McDermot Avenue, University of Manitoba, Winnipeg, MB R3E 3P4, Canada.
Source: Viruses [Viruses] 2021 Feb 12; Vol. 13 (2). Date of Electronic Publication: 2021 Feb 12.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1999-4915
DOI:10.3390/v13020289