Single-molecule FRET imaging of GPCR dimers in living cells.

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Title: Single-molecule FRET imaging of GPCR dimers in living cells.
Authors: Asher WB; Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Molecular Pharmacology and Therapeutics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA., Geggier P; Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA., Holsey MD; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.; Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Gilmore GT; Department of Chemistry, University of Akron, Akron, OH, USA., Pati AK; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Meszaros J; Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA., Terry DS; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Mathiasen S; Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA., Kaliszewski MJ; Department of Chemistry, University of Akron, Akron, OH, USA., McCauley MD; Department of Chemistry, University of Akron, Akron, OH, USA., Govindaraju A; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA., Zhou Z; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; Department of Chemistry, Queensborough Community College, The City University of New York, Bayside, NY, USA., Harikumar KG; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Scottsdale, AZ, USA., Jaqaman K; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Miller LJ; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Scottsdale, AZ, USA., Smith AW; Department of Chemistry, University of Akron, Akron, OH, USA., Blanchard SC; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA. scott.blanchard@stjude.org.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA. scott.blanchard@stjude.org., Javitch JA; Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. jonathan.javitch@nyspi.columbia.edu.; Department of Molecular Pharmacology and Therapeutics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. jonathan.javitch@nyspi.columbia.edu.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA. jonathan.javitch@nyspi.columbia.edu.; Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. jonathan.javitch@nyspi.columbia.edu.
Source: Nature methods [Nat Methods] 2021 Apr; Vol. 18 (4), pp. 397-405. Date of Electronic Publication: 2021 Mar 08.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1548-7105
DOI:10.1038/s41592-021-01081-y