Upregulation of ACE2 and TMPRSS2 by particulate matter and idiopathic pulmonary fibrosis: a potential role in severe COVID-19.

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Title: Upregulation of ACE2 and TMPRSS2 by particulate matter and idiopathic pulmonary fibrosis: a potential role in severe COVID-19.
Authors: Li HH; Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Linong St., Beitou Dist., Taipei, 112, Taiwan.; Department of Respiratory Therapy, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Liu CC; Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Linong St., Beitou Dist., Taipei, 112, Taiwan.; Division of Traumatology, Emergency Department, Taipei Veteran General Hospital, Taipei, Taiwan.; Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Hsu TW; Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Linong St., Beitou Dist., Taipei, 112, Taiwan.; Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan., Lin JH; Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Linong St., Beitou Dist., Taipei, 112, Taiwan.; Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan., Hsu JW; Division of Traumatology, Emergency Department, Taipei Veteran General Hospital, Taipei, Taiwan.; Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Li AF; Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, Taiwan., Yeh YC; Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, Taiwan., Hung SC; Institute of New Drug Development, Biomedical Sciences, China Medical University, 7F, No. 6, Xueshi Rd., North Dist., Taichung, 404, Taiwan. hung3340@gmail.com.; Integrative Stem Cell Center, Department of Orthopedics, China Medical University Hospital, Taichung, Taiwan. hung3340@gmail.com.; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan. hung3340@gmail.com., Hsu HS; Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Linong St., Beitou Dist., Taipei, 112, Taiwan. hsuhs@vghtpe.gov.tw.; Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan. hsuhs@vghtpe.gov.tw.
Source: Particle and fibre toxicology [Part Fibre Toxicol] 2021 Mar 11; Vol. 18 (1), pp. 11. Date of Electronic Publication: 2021 Mar 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101236354 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-8977 (Electronic) Linking ISSN: 17438977 NLM ISO Abbreviation: Part Fibre Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1743-8977
DOI:10.1186/s12989-021-00404-3