Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade.

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Title:	Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade.
Authors:	Lecocq Q; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., Awad RM; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., De Vlaeminck Y; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., de Mey W; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., Ertveldt T; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., Goyvaerts C; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., Raes G; Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium.; Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium., Thielemans K; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., Keyaerts M; In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium; and.; Nuclear Medicine Department, UZ Brussel, Brussels, Belgium., Devoogdt N; In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium; and nick.devoogdt@vub.be karine.breckpot@vub.be., Breckpot K; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium.
Source:	Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2021 Nov; Vol. 62 (11), pp. 1638-1644. Date of Electronic Publication: 2021 Mar 12.
Publication Type:	Journal Article
Journal Info:	Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med
Database:	MEDLINE Ultimate

Description
ISSN:	1535-5667
DOI:	10.2967/jnumed.120.258871