Protective Effects of Novel Substituted Triazinoindole Inhibitors of Aldose Reductase and Epalrestat in Neuron-like PC12 Cells and BV2 Rodent Microglial Cells Exposed to Toxic Models of Oxidative Stress: Comparison with the Pyridoindole Antioxidant Stobadine.

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Title: Protective Effects of Novel Substituted Triazinoindole Inhibitors of Aldose Reductase and Epalrestat in Neuron-like PC12 Cells and BV2 Rodent Microglial Cells Exposed to Toxic Models of Oxidative Stress: Comparison with the Pyridoindole Antioxidant Stobadine.
Authors: Elmazoglu Z; Cellular Stress Response and Signal Transduction Research Laboratory, Faculty of Medicine, Department of Medical Pharmacology, Gazi University, Beşevler, 06500, Ankara, Turkey., Prnova MS; Institute of Experimental Pharmacology and Toxicology, CEM, Slovak Academy of Sciences, Dubravska cesta 9, 84104, Bratislava, Slovakia., Stefek M; Institute of Experimental Pharmacology and Toxicology, CEM, Slovak Academy of Sciences, Dubravska cesta 9, 84104, Bratislava, Slovakia., Ceylan AF; Department of Medical Pharmacology, Faculty of Medicine, Ankara Yildirim Beyazit University Bilkent, 06800, Ankara, Turkey., Aschner M; Albert Einstein College of Medicine, Jack and Pearl Resnick Campus, Bronx, NY, 10461, USA., Rangel-López E; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología Y Neurocirugía, S.S.A, 14269, Mexico City, Mexico., Santamaria A; Laboratorio de Aminoácidos Excitadores, Instituto Nacional de Neurología Y Neurocirugía, S.S.A, 14269, Mexico City, Mexico. absada@yahoo.com., Karasu C; Cellular Stress Response and Signal Transduction Research Laboratory, Faculty of Medicine, Department of Medical Pharmacology, Gazi University, Beşevler, 06500, Ankara, Turkey. cimenkrs@gmail.com.
Source: Neurotoxicity research [Neurotox Res] 2021 Jun; Vol. 39 (3), pp. 588-597. Date of Electronic Publication: 2021 Mar 13.
Publication Type: Comparative Study; Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 100929017 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-3524 (Electronic) Linking ISSN: 10298428 NLM ISO Abbreviation: Neurotox Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1476-3524
DOI:10.1007/s12640-021-00349-7