Hepatic sinusoidal obstruction syndrome and short-term application of 6-thioguanine in pediatric acute lymphoblastic leukemia.

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Title: Hepatic sinusoidal obstruction syndrome and short-term application of 6-thioguanine in pediatric acute lymphoblastic leukemia.
Authors: Stanulla M; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany. stanulla.martin@mh-hannover.de., Schaeffeler E; Dr. Margarete-Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; Cluster of Excellence iFIT (EXC2180) 'Image-guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany., Möricke A; Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany., Buchmann S; Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany., Zimmermann M; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany., Igel S; Dr. Margarete-Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany., Schmiegelow K; Department of Pediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Copenhagen, Denmark., Flotho C; Department of Pediatric Hematology and Oncology, University Hospital Freiburg, Freiburg, Germany., Hartmann H; Department of Pediatric Kidney, Liver, and Metabolic Diseases, Hannover Medical School, Hannover, Germany., Illsinger S; Department of Pediatric Kidney, Liver, and Metabolic Diseases, Hannover Medical School, Hannover, Germany., Sauerbrey A; Pediatric Clinics, Helios Hospital, Erfurt, Germany., Junk SV; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany., Schütte P; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany., Hinze L; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany., Lauten M; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany., Modlich S; Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany., Kolb R; University Children's Hospital, Oldenburg, Germany., Rossig C; Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Schwabe G; Carl Thiem Hospital, Pediatric Clinics, Cottbus, Germany., Gnekow AK; Pediatric Clinics, University Hospital Augsburg, Augsburg, Germany., Fleischhack G; Pediatrics III, Pediatric Hematology and Oncology, University Hospital Essen, Essen, Germany., Schlegel PG; Pediatric Hematology and Oncology and Stem Cell Transplantation, University Hospital Würzburg, Würzburg, Germany., Schünemann HJ; Departments of Health Research Methods, Evidence, and Impact and of Medicine, McMaster University, Hamilton, ON, Canada., Kratz CP; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany., Cario G; Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany., Schrappe M; Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany., Schwab M; Dr. Margarete-Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; Cluster of Excellence iFIT (EXC2180) 'Image-guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany.; Departments of Clinical Pharmacology, and of Pharmacy and Biochemistry, University of Tübingen, Tübingen, Germany.
Source: Leukemia [Leukemia] 2021 Sep; Vol. 35 (9), pp. 2650-2657. Date of Electronic Publication: 2021 Mar 13.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Stanulla+M%22">Stanulla M</searchLink>; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany. stanulla.martin@mh-hannover.de.<br /><searchLink fieldCode="AU" term="%22Schaeffeler+E%22">Schaeffeler E</searchLink>; Dr. Margarete-Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; Cluster of Excellence iFIT (EXC2180) 'Image-guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Möricke+A%22">Möricke A</searchLink>; Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Buchmann+S%22">Buchmann S</searchLink>; Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Zimmermann+M%22">Zimmermann M</searchLink>; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Igel+S%22">Igel S</searchLink>; Dr. Margarete-Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.<br /><searchLink fieldCode="AU" term="%22Schmiegelow+K%22">Schmiegelow K</searchLink>; Department of Pediatrics and Adolescent Medicine, University Hospital Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Flotho+C%22">Flotho C</searchLink>; Department of Pediatric Hematology and Oncology, University Hospital Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hartmann+H%22">Hartmann H</searchLink>; Department of Pediatric Kidney, Liver, and Metabolic Diseases, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Illsinger+S%22">Illsinger S</searchLink>; Department of Pediatric Kidney, Liver, and Metabolic Diseases, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Sauerbrey+A%22">Sauerbrey A</searchLink>; Pediatric Clinics, Helios Hospital, Erfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Junk+SV%22">Junk SV</searchLink>; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Schütte+P%22">Schütte P</searchLink>; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Hinze+L%22">Hinze L</searchLink>; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Lauten+M%22">Lauten M</searchLink>; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Modlich+S%22">Modlich S</searchLink>; Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Kolb+R%22">Kolb R</searchLink>; University Children's Hospital, Oldenburg, Germany.<br /><searchLink fieldCode="AU" term="%22Rossig+C%22">Rossig C</searchLink>; Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Schwabe+G%22">Schwabe G</searchLink>; Carl Thiem Hospital, Pediatric Clinics, Cottbus, Germany.<br /><searchLink fieldCode="AU" term="%22Gnekow+AK%22">Gnekow AK</searchLink>; Pediatric Clinics, University Hospital Augsburg, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Fleischhack+G%22">Fleischhack G</searchLink>; Pediatrics III, Pediatric Hematology and Oncology, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Schlegel+PG%22">Schlegel PG</searchLink>; Pediatric Hematology and Oncology and Stem Cell Transplantation, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schünemann+HJ%22">Schünemann HJ</searchLink>; Departments of Health Research Methods, Evidence, and Impact and of Medicine, McMaster University, Hamilton, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Kratz+CP%22">Kratz CP</searchLink>; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Cario+G%22">Cario G</searchLink>; Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Schrappe+M%22">Schrappe M</searchLink>; Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Schwab+M%22">Schwab M</searchLink>; Dr. Margarete-Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; Cluster of Excellence iFIT (EXC2180) 'Image-guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany.; Departments of Clinical Pharmacology, and of Pharmacy and Biochemistry, University of Tübingen, Tübingen, Germany.
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