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The G Protein Biased Small Molecule Apelin Agonist CMF-019 is Disease Modifying in Endothelial Cell Apoptosis In Vitro and Induces Vasodilatation Without Desensitisation In Vivo.

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Title: The G Protein Biased Small Molecule Apelin Agonist CMF-019 is Disease Modifying in Endothelial Cell Apoptosis In Vitro and Induces Vasodilatation Without Desensitisation In Vivo.
Authors: Read C; Department of Medicine, Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Nyimanu D; Department of Medicine, Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Yang P; Department of Medicine, Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Kuc RE; Department of Medicine, Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Williams TL; Department of Medicine, Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Fitzpatrick CM; School of Chemistry and Astbury Centre for Structural Biology, University of Leeds, Leeds, United Kingdom., Foster R; School of Chemistry and Astbury Centre for Structural Biology, University of Leeds, Leeds, United Kingdom., Glen RC; Department of Chemistry, Centre for Molecular Informatics, University of Cambridge, Cambridge, United Kingdom.; Division of Systems Medicine, Department of Metabolism Digestion and Reproduction, Imperial College London, London, United Kingdom., Maguire JJ; Department of Medicine, Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Davenport AP; Department of Medicine, Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.
Source: Frontiers in pharmacology [Front Pharmacol] 2021 Jan 21; Vol. 11, pp. 588669. Date of Electronic Publication: 2021 Jan 21 (Print Publication: 2020).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media]%22">Frontiers Media] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101548923 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1663-9812 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216639812%22">16639812 </searchLink><i>NLM ISO Abbreviation: </i>Front Pharmacol <i>Subsets: </i>PubMed not MEDLINE
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