Identification of small molecules that mitigate vincristine-induced neurotoxicity while sensitizing leukemia cells to vincristine.
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| Title: | Identification of small molecules that mitigate vincristine-induced neurotoxicity while sensitizing leukemia cells to vincristine. |
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| Authors: | Diouf B; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Wing C; Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, Illinois, USA., Panetta JC; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Eddins D; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Lin W; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Yang W; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Fan Y; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Pei D; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Cheng C; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Delaney SM; Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, Illinois, USA., Zhang W; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Bonten EJ; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Crews KR; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Paugh SW; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Li L; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Freeman BB 3rd; Preclinical Pharmacokinetics Shared Resource, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Autry RJ; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Beard JA; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Ferguson DC; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Janke LJ; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Ness KK; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Chen T; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Zakharenko SS; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Jeha S; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Pui CH; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Relling MV; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Eileen Dolan M; Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, Illinois, USA., Evans WE; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. |
| Source: | Clinical and translational science [Clin Transl Sci] 2021 Jul; Vol. 14 (4), pp. 1490-1504. Date of Electronic Publication: 2021 May 31. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1752-8062 |
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| DOI: | 10.1111/cts.13012 |
