Targeting backdoor androgen synthesis through AKR1C3 inhibition: A presurgical hormonal ablative neoadjuvant trial in high-risk localized prostate cancer.
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| Title: | Targeting backdoor androgen synthesis through AKR1C3 inhibition: A presurgical hormonal ablative neoadjuvant trial in high-risk localized prostate cancer. |
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| Authors: | Graham LS; Division of Oncology, Department of Medicine, University of Washington, Seattle, Washington, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., True LD; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA., Gulati R; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Schade GR; Department of Urology, University of Washington, Seattle, Washington, USA., Wright J; Department of Urology, University of Washington, Seattle, Washington, USA., Grivas P; Division of Oncology, Department of Medicine, University of Washington, Seattle, Washington, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Yezefski T; Division of Oncology, Department of Medicine, University of Washington, Seattle, Washington, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Nega K; Division of Oncology, Department of Medicine, University of Washington, Seattle, Washington, USA., Alexander K; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Hou WM; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Yu EY; Division of Oncology, Department of Medicine, University of Washington, Seattle, Washington, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Montgomery B; Division of Oncology, Department of Medicine, University of Washington, Seattle, Washington, USA.; Geriatric Research Education and Clinical Care, VA Puget Sound Health Care System, Seattle, Washington, USA., Mostaghel EA; Division of Oncology, Department of Medicine, University of Washington, Seattle, Washington, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Geriatric Research Education and Clinical Care, VA Puget Sound Health Care System, Seattle, Washington, USA., Matsumoto AA; Geriatric Research Education and Clinical Care, VA Puget Sound Health Care System, Seattle, Washington, USA., Marck B; Geriatric Research Education and Clinical Care, VA Puget Sound Health Care System, Seattle, Washington, USA., Sharifi N; Genitourinary Malignancies Research Center, Cleveland Clinic, Cleveland, Ohio, USA., Ellis WJ; Department of Urology, University of Washington, Seattle, Washington, USA., Reder NP; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.; Department of Mechanical Engineering, University of Washington, Seattle, Washington, USA., Lin DW; Department of Urology, University of Washington, Seattle, Washington, USA., Nelson PS; Division of Oncology, Department of Medicine, University of Washington, Seattle, Washington, USA.; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Schweizer MT; Division of Oncology, Department of Medicine, University of Washington, Seattle, Washington, USA.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. |
| Source: | The Prostate [Prostate] 2021 May; Vol. 81 (7), pp. 418-426. Date of Electronic Publication: 2021 Mar 23. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8101368 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0045 (Electronic) Linking ISSN: 02704137 NLM ISO Abbreviation: Prostate Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1097-0045 |
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| DOI: | 10.1002/pros.24118 |
