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NaV1.2 EFL domain allosterically enhances Ca2+ binding to sites I and II of WT and pathogenic calmodulin mutants bound to the channel CTD.

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Title: NaV1.2 EFL domain allosterically enhances Ca2+ binding to sites I and II of WT and pathogenic calmodulin mutants bound to the channel CTD.
Authors: Mahling R; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA., Hovey L; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA., Isbell HM; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA., Marx DC; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA., Miller MS; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA., Kilpatrick AM; Department of Physics and Astronomy, Drake University, Des Moines, IA 50311-4516, USA., Weaver LD; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA., Yoder JB; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA., Kim EH; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA., Andresen CNJ; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA., Li S; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA., Shea MA; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA. Electronic address: madeline-shea@uiowa.edu.
Source: Structure (London, England : 1993) [Structure] 2021 Dec 02; Vol. 29 (12), pp. 1339-1356.e7. Date of Electronic Publication: 2021 Mar 25.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Na<subscript>V</subscript>1.2 EFL domain allosterically enhances Ca<superscript>2+</superscript> binding to sites I and II of WT and pathogenic calmodulin mutants bound to the channel CTD.
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  Data: <searchLink fieldCode="AU" term="%22Mahling+R%22">Mahling R</searchLink>; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA.<br /><searchLink fieldCode="AU" term="%22Hovey+L%22">Hovey L</searchLink>; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA.<br /><searchLink fieldCode="AU" term="%22Isbell+HM%22">Isbell HM</searchLink>; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA.<br /><searchLink fieldCode="AU" term="%22Marx+DC%22">Marx DC</searchLink>; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA.<br /><searchLink fieldCode="AU" term="%22Miller+MS%22">Miller MS</searchLink>; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA.<br /><searchLink fieldCode="AU" term="%22Kilpatrick+AM%22">Kilpatrick AM</searchLink>; Department of Physics and Astronomy, Drake University, Des Moines, IA 50311-4516, USA.<br /><searchLink fieldCode="AU" term="%22Weaver+LD%22">Weaver LD</searchLink>; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA.<br /><searchLink fieldCode="AU" term="%22Yoder+JB%22">Yoder JB</searchLink>; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA.<br /><searchLink fieldCode="AU" term="%22Kim+EH%22">Kim EH</searchLink>; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA.<br /><searchLink fieldCode="AU" term="%22Andresen+CNJ%22">Andresen CNJ</searchLink>; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA.<br /><searchLink fieldCode="AU" term="%22Shea+MA%22">Shea MA</searchLink>; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242-1109, USA. Electronic address: madeline-shea@uiowa.edu.
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  Data: <searchLink fieldCode="JN" term="%22101087697%22">Structure (London, England : 1993)</searchLink> [Structure] 2021 Dec 02; Vol. 29 (12), pp. 1339-1356.e7. <i>Date of Electronic Publication: </i>2021 Mar 25.
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