A single subcutaneous or intranasal immunization with adenovirus-based SARS-CoV-2 vaccine induces robust humoral and cellular immune responses in mice.
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| Title: | A single subcutaneous or intranasal immunization with adenovirus-based SARS-CoV-2 vaccine induces robust humoral and cellular immune responses in mice. |
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| Authors: | Kim E; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Weisel FJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Balmert SC; Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Khan MS; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA., Huang S; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Erdos G; Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Kenniston TW; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Carey CD; Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Joachim SM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Conter LJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Weisel NM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Okba NMA; Department of Viroscience, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands., Haagmans BL; Department of Viroscience, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands., Percivalle E; Molecular Virology Unit, Microbiology and Virology Department, IRCCS Policlinico San Matteo, Pavia, Italy., Cassaniti I; Molecular Virology Unit, Microbiology and Virology Department, IRCCS Policlinico San Matteo, Pavia, Italy., Baldanti F; Molecular Virology Unit, Microbiology and Virology Department, IRCCS Policlinico San Matteo, Pavia, Italy.; Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy., Korkmaz E; Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh Swanson School of Engineering, Pittsburgh, PA, USA., Shlomchik MJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Falo LD Jr; Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Bioengineering, University of Pittsburgh Swanson School of Engineering, Pittsburgh, PA, USA.; Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA, USA.; The McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Gambotto A; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Medicine, Division of Infectious Disease, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. |
| Source: | European journal of immunology [Eur J Immunol] 2021 Jul; Vol. 51 (7), pp. 1774-1784. Date of Electronic Publication: 2021 May 06. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 1273201 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4141 (Electronic) Linking ISSN: 00142980 NLM ISO Abbreviation: Eur J Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1521-4141 |
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| DOI: | 10.1002/eji.202149167 |
