Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase.

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Title: Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase.
Authors: Dawson CD; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Irwin SM; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA., Backman LRF; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Le C; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA., Wang JX; Harvard Center for Mass Spectrometry, Faculty of Arts and Sciences Division of Science, Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA., Vennelakanti V; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Yang Z; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Kulik HJ; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: hjkulik@mit.edu., Drennan CL; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: cdrennan@mit.edu., Balskus EP; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA; Broad Institute, Cambridge, MA 02139, USA. Electronic address: balskus@chemistry.harvard.edu.
Source: Cell chemical biology [Cell Chem Biol] 2021 Sep 16; Vol. 28 (9), pp. 1333-1346.e7. Date of Electronic Publication: 2021 Mar 26.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2451-9448
DOI:10.1016/j.chembiol.2021.03.001