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Single-cell atlas of hepatic T cells reveals expansion of liver-resident naive-like CD4+ T cells in primary sclerosing cholangitis.

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Title: Single-cell atlas of hepatic T cells reveals expansion of liver-resident naive-like CD4+ T cells in primary sclerosing cholangitis.
Authors: Poch T; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Krause J; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Casar C; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Bioinformatics Core, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Liwinski T; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Immunology Department, Weizmann Institute of Science, Rehovot 7610001 Israel., Glau L; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Kaufmann M; Institute of Neuroimmunology and Multiple Sclerosis, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Ahrenstorf AE; Virus Immunology Department, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg 20246 Germany., Hess LU; Virus Immunology Department, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg 20246 Germany., Ziegler AE; Virus Immunology Department, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg 20246 Germany., Martrus G; Virus Immunology Department, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg 20246 Germany., Lunemann S; Virus Immunology Department, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg 20246 Germany., Sebode M; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Li J; Department for General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Schwinge D; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Krebs CF; III. Department of Medicine, Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel 24105 Germany., Friese MA; Institute of Neuroimmunology and Multiple Sclerosis, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Oldhafer KJ; Department of General and Abdominal Surgery, Asklepios Hospital Barmbek, Semmelweis University of Medicine Hamburg, Germany., Fischer L; Department for Visceral Transplant Surgery, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Altfeld M; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Virus Immunology Department, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg 20246 Germany., Lohse AW; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Huber S; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Tolosa E; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany., Gagliani N; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Department for General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Immunology and Allergy Unit, Department of Medicine Solna, Karolinska Institute, Stockholm 17177 Sweden. Electronic address: n.gagliani@uke.de., Schramm C; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Martin Zeitz Center for Rare Diseases, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany. Electronic address: c.schramm@uke.de.
Source: Journal of hepatology [J Hepatol] 2021 Aug; Vol. 75 (2), pp. 414-423. Date of Electronic Publication: 2021 Mar 24.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-cell atlas of hepatic T cells reveals expansion of liver-resident naive-like CD4<superscript>+</superscript> T cells in primary sclerosing cholangitis.
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  Data: <searchLink fieldCode="AU" term="%22Poch+T%22">Poch T</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Krause+J%22">Krause J</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Casar+C%22">Casar C</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Bioinformatics Core, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Liwinski+T%22">Liwinski T</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Immunology Department, Weizmann Institute of Science, Rehovot 7610001 Israel.<br /><searchLink fieldCode="AU" term="%22Glau+L%22">Glau L</searchLink>; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Kaufmann+M%22">Kaufmann M</searchLink>; Institute of Neuroimmunology and Multiple Sclerosis, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Ahrenstorf+AE%22">Ahrenstorf AE</searchLink>; Virus Immunology Department, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Hess+LU%22">Hess LU</searchLink>; Virus Immunology Department, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Ziegler+AE%22">Ziegler AE</searchLink>; Virus Immunology Department, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Martrus+G%22">Martrus G</searchLink>; Virus Immunology Department, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Lunemann+S%22">Lunemann S</searchLink>; Virus Immunology Department, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Sebode+M%22">Sebode M</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department for General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Schwinge+D%22">Schwinge D</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Krebs+CF%22">Krebs CF</searchLink>; III. Department of Medicine, Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Franke+A%22">Franke A</searchLink>; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel 24105 Germany.<br /><searchLink fieldCode="AU" term="%22Friese+MA%22">Friese MA</searchLink>; Institute of Neuroimmunology and Multiple Sclerosis, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Oldhafer+KJ%22">Oldhafer KJ</searchLink>; Department of General and Abdominal Surgery, Asklepios Hospital Barmbek, Semmelweis University of Medicine Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Fischer+L%22">Fischer L</searchLink>; Department for Visceral Transplant Surgery, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Altfeld+M%22">Altfeld M</searchLink>; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Virus Immunology Department, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Lohse+AW%22">Lohse AW</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Huber+S%22">Huber S</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Tolosa+E%22">Tolosa E</searchLink>; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany.<br /><searchLink fieldCode="AU" term="%22Gagliani+N%22">Gagliani N</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Department for General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Immunology and Allergy Unit, Department of Medicine Solna, Karolinska Institute, Stockholm 17177 Sweden. Electronic address: n.gagliani@uke.de.<br /><searchLink fieldCode="AU" term="%22Schramm+C%22">Schramm C</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany; Martin Zeitz Center for Rare Diseases, University Medical Center Hamburg-Eppendorf, Hamburg 20246 Germany. Electronic address: c.schramm@uke.de.
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  Data: <searchLink fieldCode="JN" term="%228503886%22">Journal of hepatology</searchLink> [J Hepatol] 2021 Aug; Vol. 75 (2), pp. 414-423. <i>Date of Electronic Publication: </i>2021 Mar 24.
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