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Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia.

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Title: Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia.
Authors: Braga L; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK., Ali H; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK., Secco I; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK., Chiavacci E; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK., Neves G; MRC Centre for Neurodevelopmental Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Goldhill D; Department of Infectious Diseases, Imperial College London, London, UK., Penn R; Department of Infectious Diseases, Imperial College London, London, UK., Jimenez-Guardeño JM; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, UK., Ortega-Prieto AM; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, UK., Bussani R; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Cannatà A; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK., Rizzari G; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK., Collesi C; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy., Schneider E; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK.; International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy., Arosio D; Istituto di Biofisica (IBF), Consiglio Nazionale delle Ricerche (CNR), Trento, Italy., Shah AM; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK., Barclay WS; Department of Infectious Diseases, Imperial College London, London, UK., Malim MH; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, UK., Burrone J; MRC Centre for Neurodevelopmental Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Giacca M; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK. mauro.giacca@kcl.ac.uk.; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy. mauro.giacca@kcl.ac.uk.; International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy. mauro.giacca@kcl.ac.uk.
Source: Nature [Nature] 2021 Jun; Vol. 594 (7861), pp. 88-93. Date of Electronic Publication: 2021 Apr 07.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia.
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  Data: <searchLink fieldCode="AU" term="%22Braga+L%22">Braga L</searchLink>; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK.<br /><searchLink fieldCode="AU" term="%22Ali+H%22">Ali H</searchLink>; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK.<br /><searchLink fieldCode="AU" term="%22Secco+I%22">Secco I</searchLink>; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK.<br /><searchLink fieldCode="AU" term="%22Chiavacci+E%22">Chiavacci E</searchLink>; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK.<br /><searchLink fieldCode="AU" term="%22Neves+G%22">Neves G</searchLink>; MRC Centre for Neurodevelopmental Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Goldhill+D%22">Goldhill D</searchLink>; Department of Infectious Diseases, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Penn+R%22">Penn R</searchLink>; Department of Infectious Diseases, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Jimenez-Guardeño+JM%22">Jimenez-Guardeño JM</searchLink>; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ortega-Prieto+AM%22">Ortega-Prieto AM</searchLink>; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Bussani+R%22">Bussani R</searchLink>; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Cannatà+A%22">Cannatà A</searchLink>; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK.<br /><searchLink fieldCode="AU" term="%22Rizzari+G%22">Rizzari G</searchLink>; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK.<br /><searchLink fieldCode="AU" term="%22Collesi+C%22">Collesi C</searchLink>; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Schneider+E%22">Schneider E</searchLink>; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK.; International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Arosio+D%22">Arosio D</searchLink>; Istituto di Biofisica (IBF), Consiglio Nazionale delle Ricerche (CNR), Trento, Italy.<br /><searchLink fieldCode="AU" term="%22Shah+AM%22">Shah AM</searchLink>; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK.<br /><searchLink fieldCode="AU" term="%22Barclay+WS%22">Barclay WS</searchLink>; Department of Infectious Diseases, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Malim+MH%22">Malim MH</searchLink>; Department of Infectious Diseases, School of Immunology & Microbial Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Burrone+J%22">Burrone J</searchLink>; MRC Centre for Neurodevelopmental Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Giacca+M%22">Giacca M</searchLink>; King's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, London, UK. mauro.giacca@kcl.ac.uk.; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy. mauro.giacca@kcl.ac.uk.; International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy. mauro.giacca@kcl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2021 Jun; Vol. 594 (7861), pp. 88-93. <i>Date of Electronic Publication: </i>2021 Apr 07.
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