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Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits.

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Title: Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits.
Authors: Arveseth CD; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Happ JT; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Hedeen DS; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Zhu JF; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Capener JL; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Klatt Shaw D; Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Deshpande I; Department of Pharmaceutical Chemistry, Department of Anaesthesia and Perioperative Care, University of California, San Francisco, California, United States of America., Liang J; Department of Pharmaceutical Chemistry, Department of Anaesthesia and Perioperative Care, University of California, San Francisco, California, United States of America., Xu J; Department of Cellular and Molecular Pharmacology, Quantitative Biosciences Institute, University of California, San Francisco, California, United States of America.; J. David Gladstone Institutes, San Francisco, California, United States of America., Stubben SL; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Nelson IB; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Walker MF; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Kawakami K; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan., Inoue A; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan., Krogan NJ; Department of Cellular and Molecular Pharmacology, Quantitative Biosciences Institute, University of California, San Francisco, California, United States of America.; J. David Gladstone Institutes, San Francisco, California, United States of America., Grunwald DJ; Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America., Hüttenhain R; Department of Cellular and Molecular Pharmacology, Quantitative Biosciences Institute, University of California, San Francisco, California, United States of America.; J. David Gladstone Institutes, San Francisco, California, United States of America., Manglik A; Department of Pharmaceutical Chemistry, Department of Anaesthesia and Perioperative Care, University of California, San Francisco, California, United States of America., Myers BR; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.
Source: PLoS biology [PLoS Biol] 2021 Apr 22; Vol. 19 (4), pp. e3001191. Date of Electronic Publication: 2021 Apr 22 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits.
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  Data: <searchLink fieldCode="AU" term="%22Arveseth+CD%22">Arveseth CD</searchLink>; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Happ+JT%22">Happ JT</searchLink>; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Hedeen+DS%22">Hedeen DS</searchLink>; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Zhu+JF%22">Zhu JF</searchLink>; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Capener+JL%22">Capener JL</searchLink>; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Klatt+Shaw+D%22">Klatt Shaw D</searchLink>; Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Deshpande+I%22">Deshpande I</searchLink>; Department of Pharmaceutical Chemistry, Department of Anaesthesia and Perioperative Care, University of California, San Francisco, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Liang+J%22">Liang J</searchLink>; Department of Pharmaceutical Chemistry, Department of Anaesthesia and Perioperative Care, University of California, San Francisco, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; Department of Cellular and Molecular Pharmacology, Quantitative Biosciences Institute, University of California, San Francisco, California, United States of America.; J. David Gladstone Institutes, San Francisco, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Stubben+SL%22">Stubben SL</searchLink>; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Nelson+IB%22">Nelson IB</searchLink>; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Walker+MF%22">Walker MF</searchLink>; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Kawakami+K%22">Kawakami K</searchLink>; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan.<br /><searchLink fieldCode="AU" term="%22Inoue+A%22">Inoue A</searchLink>; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Miyagi, Japan.<br /><searchLink fieldCode="AU" term="%22Krogan+NJ%22">Krogan NJ</searchLink>; Department of Cellular and Molecular Pharmacology, Quantitative Biosciences Institute, University of California, San Francisco, California, United States of America.; J. David Gladstone Institutes, San Francisco, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Grunwald+DJ%22">Grunwald DJ</searchLink>; Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Hüttenhain+R%22">Hüttenhain R</searchLink>; Department of Cellular and Molecular Pharmacology, Quantitative Biosciences Institute, University of California, San Francisco, California, United States of America.; J. David Gladstone Institutes, San Francisco, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Manglik+A%22">Manglik A</searchLink>; Department of Pharmaceutical Chemistry, Department of Anaesthesia and Perioperative Care, University of California, San Francisco, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Myers+BR%22">Myers BR</searchLink>; Department of Oncological Sciences, Department of Biochemistry, Department of Bioengineering, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101183755%22">PLoS biology</searchLink> [PLoS Biol] 2021 Apr 22; Vol. 19 (4), pp. e3001191. <i>Date of Electronic Publication: </i>2021 Apr 22 (<i>Print Publication: </i>2021).
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