Supramolecular Cylinders Target Bulge Structures in the 5' UTR of the RNA Genome of SARS-CoV-2 and Inhibit Viral Replication*.

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Title: Supramolecular Cylinders Target Bulge Structures in the 5' UTR of the RNA Genome of SARS-CoV-2 and Inhibit Viral Replication*.
Authors: Melidis L; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Hill HJ; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Coltman NJ; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Davies SP; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Winczura K; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Chauhan T; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Craig JS; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Garai A; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Hooper CAJ; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Egan RT; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., McKeating JA; Nuffield Department of Medicine & Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), Oxford University, Oxford, OX3 7BN, UK., Hodges NJ; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Stamataki Z; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Grzechnik P; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Hannon MJ; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Aug 09; Vol. 60 (33), pp. 18144-18151. Date of Electronic Publication: 2021 Jul 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1521-3773
DOI:10.1002/anie.202104179