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RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes.

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Title: RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes.
Authors: Heib T; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany., Hermanns HM; Department of Internal Medicine II, Hepatology Research Laboratory, University Hospital Würzburg, 97080 Würzburg, Germany., Manukjan G; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany., Englert M; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany., Kusch C; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany., Becker IC; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany., Gerber A; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany., Wackerbarth LM; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany., Burkard P; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany., Dandekar T; Department of Bioinformatics, Biocenter, University of Würzburg, 97074 Würzburg, Germany., Balkenhol J; Department of Internal Medicine II, Hepatology Research Laboratory, University Hospital Würzburg, 97080 Würzburg, Germany; Department of Bioinformatics, Biocenter, University of Würzburg, 97074 Würzburg, Germany., Jahn D; Department of Internal Medicine II, Hepatology Research Laboratory, University Hospital Würzburg, 97080 Würzburg, Germany., Beck S; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany., Meub M; Department of Biotechnology and Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany., Dütting S; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany., Stigloher C; Imaging Core Facility, Biocenter, University of Würzburg, 97074 Würzburg, Germany., Sauer M; Department of Biotechnology and Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany., Cherpokova D; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany., Schulze H; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany., Brakebusch C; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, 2200 Copenhagen, Denmark., Nieswandt B; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany. Electronic address: bernhard.nieswandt@virchow.uni-wuerzburg.de., Nagy Z; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany., Pleines I; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany. Electronic address: pleines_i@ukw.de.
Source: Cell reports [Cell Rep] 2021 May 11; Vol. 35 (6), pp. 109102.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes.
– Name: Author
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  Data: <searchLink fieldCode="AU" term="%22Heib+T%22">Heib T</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hermanns+HM%22">Hermanns HM</searchLink>; Department of Internal Medicine II, Hepatology Research Laboratory, University Hospital Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Manukjan+G%22">Manukjan G</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Englert+M%22">Englert M</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kusch+C%22">Kusch C</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Becker+IC%22">Becker IC</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gerber+A%22">Gerber A</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Wackerbarth+LM%22">Wackerbarth LM</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Burkard+P%22">Burkard P</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Dandekar+T%22">Dandekar T</searchLink>; Department of Bioinformatics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Balkenhol+J%22">Balkenhol J</searchLink>; Department of Internal Medicine II, Hepatology Research Laboratory, University Hospital Würzburg, 97080 Würzburg, Germany; Department of Bioinformatics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jahn+D%22">Jahn D</searchLink>; Department of Internal Medicine II, Hepatology Research Laboratory, University Hospital Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Beck+S%22">Beck S</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Meub+M%22">Meub M</searchLink>; Department of Biotechnology and Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Dütting+S%22">Dütting S</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Stigloher+C%22">Stigloher C</searchLink>; Imaging Core Facility, Biocenter, University of Würzburg, 97074 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sauer+M%22">Sauer M</searchLink>; Department of Biotechnology and Biophysics, Biocenter, University of Würzburg, 97074 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Cherpokova+D%22">Cherpokova D</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schulze+H%22">Schulze H</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Brakebusch+C%22">Brakebusch C</searchLink>; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, 2200 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Nieswandt+B%22">Nieswandt B</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany. Electronic address: bernhard.nieswandt@virchow.uni-wuerzburg.de.<br /><searchLink fieldCode="AU" term="%22Nagy+Z%22">Nagy Z</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Pleines+I%22">Pleines I</searchLink>; Institute of Experimental Biomedicine, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Rudolf Virchow Center, University of Würzburg, 97080 Würzburg, Germany. Electronic address: pleines_i@ukw.de.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2021 May 11; Vol. 35 (6), pp. 109102.
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