Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.

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Title: Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.
Authors: Schmidt NM; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Wing PAC; Nuffield Department of Medicine, Oxford University, Oxford, UK., Diniz MO; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Pallett LJ; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Swadling L; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Harris JM; Nuffield Department of Medicine, Oxford University, Oxford, UK., Burton AR; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Jeffery-Smith A; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Zakeri N; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Amin OE; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Kucykowicz S; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Heemskerk MH; Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands., Davidson B; Division of Surgery, University College London, London, UK.; Royal Free London NHS Foundation Trust, London, UK., Meyer T; Royal Free London NHS Foundation Trust, London, UK.; Cancer Institute, University College London, London, UK., Grove J; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Stauss HJ; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Pineda-Torra I; Division of Medicine, University College London, London, UK., Jolly C; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Jury EC; Division of Medicine, University College London, London, UK., McKeating JA; Nuffield Department of Medicine, Oxford University, Oxford, UK., Maini MK; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK. m.maini@ucl.ac.uk.
Source: Nature communications [Nat Commun] 2021 May 14; Vol. 12 (1), pp. 2814. Date of Electronic Publication: 2021 May 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-021-22967-7