Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.

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Title: Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.
Authors: Schmidt NM; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Wing PAC; Nuffield Department of Medicine, Oxford University, Oxford, UK., Diniz MO; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Pallett LJ; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Swadling L; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Harris JM; Nuffield Department of Medicine, Oxford University, Oxford, UK., Burton AR; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Jeffery-Smith A; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Zakeri N; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Amin OE; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Kucykowicz S; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Heemskerk MH; Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands., Davidson B; Division of Surgery, University College London, London, UK.; Royal Free London NHS Foundation Trust, London, UK., Meyer T; Royal Free London NHS Foundation Trust, London, UK.; Cancer Institute, University College London, London, UK., Grove J; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Stauss HJ; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Pineda-Torra I; Division of Medicine, University College London, London, UK., Jolly C; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Jury EC; Division of Medicine, University College London, London, UK., McKeating JA; Nuffield Department of Medicine, Oxford University, Oxford, UK., Maini MK; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK. m.maini@ucl.ac.uk.
Source: Nature communications [Nat Commun] 2021 May 14; Vol. 12 (1), pp. 2814. Date of Electronic Publication: 2021 May 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.
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  Data: <searchLink fieldCode="AU" term="%22Schmidt+NM%22">Schmidt NM</searchLink>; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Wing+PAC%22">Wing PAC</searchLink>; Nuffield Department of Medicine, Oxford University, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Diniz+MO%22">Diniz MO</searchLink>; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Pallett+LJ%22">Pallett LJ</searchLink>; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Swadling+L%22">Swadling L</searchLink>; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Harris+JM%22">Harris JM</searchLink>; Nuffield Department of Medicine, Oxford University, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Burton+AR%22">Burton AR</searchLink>; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Jeffery-Smith+A%22">Jeffery-Smith A</searchLink>; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Zakeri+N%22">Zakeri N</searchLink>; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Amin+OE%22">Amin OE</searchLink>; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kucykowicz+S%22">Kucykowicz S</searchLink>; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Heemskerk+MH%22">Heemskerk MH</searchLink>; Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Davidson+B%22">Davidson B</searchLink>; Division of Surgery, University College London, London, UK.; Royal Free London NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Meyer+T%22">Meyer T</searchLink>; Royal Free London NHS Foundation Trust, London, UK.; Cancer Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Grove+J%22">Grove J</searchLink>; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Stauss+HJ%22">Stauss HJ</searchLink>; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Pineda-Torra+I%22">Pineda-Torra I</searchLink>; Division of Medicine, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Jolly+C%22">Jolly C</searchLink>; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Jury+EC%22">Jury EC</searchLink>; Division of Medicine, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22McKeating+JA%22">McKeating JA</searchLink>; Nuffield Department of Medicine, Oxford University, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Maini+MK%22">Maini MK</searchLink>; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK. m.maini@ucl.ac.uk.
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