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A Novel Series of Indole Alkaloid Derivatives Inhibit Dengue and Zika Virus Infection by Interference with the Viral Replication Complex.

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Title: A Novel Series of Indole Alkaloid Derivatives Inhibit Dengue and Zika Virus Infection by Interference with the Viral Replication Complex.
Authors: Fikatas A; Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, KU Leuven, Rega Institute for Medical Research, Leuven, Belgium., Vervaeke P; Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, KU Leuven, Rega Institute for Medical Research, Leuven, Belgium., Meyen E; Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, KU Leuven, Rega Institute for Medical Research, Leuven, Belgium., Llor N; Laboratory of Organic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Institute of Biomedicine, Barcelona, Spain., Ordeix S; Laboratory of Organic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Institute of Biomedicine, Barcelona, Spain., Boonen I; Laboratory of Clinical and Epidemiological Virology, Department of Microbiology, Immunology and Transplantation, KU Leuven, Rega Institute for Medical Research, Leuven, Belgium., Bletsa M; Laboratory of Clinical and Epidemiological Virology, Department of Microbiology, Immunology and Transplantation, KU Leuven, Rega Institute for Medical Research, Leuven, Belgium., Kafetzopoulou LE; Laboratory of Clinical and Epidemiological Virology, Department of Microbiology, Immunology and Transplantation, KU Leuven, Rega Institute for Medical Research, Leuven, Belgium., Lemey P; Laboratory of Clinical and Epidemiological Virology, Department of Microbiology, Immunology and Transplantation, KU Leuven, Rega Institute for Medical Research, Leuven, Belgium., Amat M; Laboratory of Organic Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Institute of Biomedicine, Barcelona, Spain., Pannecouque C; Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, KU Leuven, Rega Institute for Medical Research, Leuven, Belgium., Schols D; Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, KU Leuven, Rega Institute for Medical Research, Leuven, Belgium.
Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Jul 16; Vol. 65 (8), pp. e0234920. Date of Electronic Publication: 2021 Jul 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1098-6596
DOI:10.1128/AAC.02349-20