Tocilizumab is safe and tolerable and reduces C-reactive protein concentrations in the plasma and cerebrospinal fluid of ALS patients.
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| Title: | Tocilizumab is safe and tolerable and reduces C-reactive protein concentrations in the plasma and cerebrospinal fluid of ALS patients. |
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| Authors: | Milligan C; Department of Neurobiology and Anatomy, Wake Forest University, Winston-Salem, North Carolina, USA., Atassi N; Department of Neurology, Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, Massachusetts, USA., Babu S; Department of Neurology, Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, Massachusetts, USA., Barohn RJ; Department of Neurology, Kansas University, Kansas City, Kansas, USA., Caress JB; Department of Neurology, Wake Forest University, Winston-Salem, North Carolina, USA., Cudkowicz ME; Department of Neurology, Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, Massachusetts, USA., Evora A; Department of Neurology, Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, Massachusetts, USA., Hawkins GA; Department of Biochemistry and Center for Precision Medicine, Wake Forest University, Winston-Salem, North Carolina, USA., Wosiski-Kuhn M; Department of Neurobiology and Anatomy, Wake Forest University, Winston-Salem, North Carolina, USA., Macklin EA; Department of Medicine, Biostatistics Center, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA., Shefner JM; Department of Neurology, Gregory W. Fulton ALS and Neuromuscular Disease Center, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Simmons Z; Department of Neurology, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA., Bowser RP; Departments of Neurology and Neurobiology, Gregory W. Fulton ALS and Neuromuscular Disease Center, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Ladha SS; Department of Neurology, Gregory W. Fulton ALS and Neuromuscular Disease Center, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA. |
| Source: | Muscle & nerve [Muscle Nerve] 2021 Sep; Vol. 64 (3), pp. 309-320. Date of Electronic Publication: 2021 Jun 24. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 7803146 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4598 (Electronic) Linking ISSN: 0148639X NLM ISO Abbreviation: Muscle Nerve Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1097-4598 |
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| DOI: | 10.1002/mus.27339 |