A phase I, open-label study evaluating the safety and pharmacokinetics of trifluridine/tipiracil in patients with advanced solid tumors and varying degrees of renal impairment.
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| Title: | A phase I, open-label study evaluating the safety and pharmacokinetics of trifluridine/tipiracil in patients with advanced solid tumors and varying degrees of renal impairment. |
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| Authors: | Saif MW; Medical Oncology, Northwell Health Cancer Institute, 1111 Marcus Avenue, Suite 216, Lake Success, NY, 11042, USA. wsaif@northwell.edu., Becerra CR; Texas Oncology, Baylor University Medical Center, Dallas, TX, USA., Fakih MG; City of Hope Comprehensive Cancer Center, Duarte, CA, USA., Sun W; Division of Oncology, University of Kansas Medical Center, Kansas City, KS, USA., Popovic L; Oncology Institute of Vojvodina, University of Novi Sad, Novi Sad, Serbia., Krishnamurthi S; Cleveland Clinic, Cleveland, OH, USA., George TJ; University of Florida Health Cancer Center, Gainesville, FL, USA., Rudek MA; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA., Shepard DR; Cleveland Clinic, Cleveland, OH, USA., Skopek J; Thomayer Hospital Prague and Department of Biophysics and Informatics, First Medical Faculty, Prague, Czech Republic., Sramek V; Fakultni Nemocnice u Sv. Anny v Brně, Anesteziologicko Resustitační Klinika, Brno, Czech Republic., Zaric B; Institute for Pulmonary Diseases of Vojvodina, University of Novi Sad, Novi Sad, Serbia., Yamamiya I; Taiho Oncology, Inc., Princeton, NJ, USA., Benhadji KA; Taiho Oncology, Inc., Princeton, NJ, USA., Hamada K; Taiho Oncology, Inc., Princeton, NJ, USA., He Y; Taiho Oncology, Inc., Princeton, NJ, USA., Rosen L; Division of Hematology-Oncology, University of California, Los Angeles, CA, USA. |
| Source: | Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2021 Sep; Vol. 88 (3), pp. 485-497. Date of Electronic Publication: 2021 Jun 07. |
| Publication Type: | Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-0843 |
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| DOI: | 10.1007/s00280-021-04308-z |
