Mouse IL-2/CD25 Fusion Protein Induces Regulatory T Cell Expansion and Immune Suppression in Preclinical Models of Systemic Lupus Erythematosus.

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Title: Mouse IL-2/CD25 Fusion Protein Induces Regulatory T Cell Expansion and Immune Suppression in Preclinical Models of Systemic Lupus Erythematosus.
Authors: Xie JH; Department of Discovery Biology, Bristol Myers Squibb, Princeton, NJ; jenny.xie@bms.com Mary.Struthers@bms.com., Zhang Y; Department of Discovery Biology, Bristol Myers Squibb, Princeton, NJ., Loubeau M; Department of Discovery Biology, Bristol Myers Squibb, Princeton, NJ., Mangan P; Department of Discovery Biology, Bristol Myers Squibb, Princeton, NJ., Heimrich E; Department of Discovery Biology, Bristol Myers Squibb, Princeton, NJ., Tovar C; Department of Discovery Biology, Bristol Myers Squibb, Princeton, NJ., Zhou X; Department of Discovery Biology, Bristol Myers Squibb, Princeton, NJ., Madia P; Department of Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Princeton, NJ., Doyle M; Department of Discovery Protein Science, Bristol Myers Squibb, Princeton, NJ., Dudhgaonkar S; Biocon-Bristol Myers Squibb Research and Development Center, Syngene International Ltd., Bangalore, India; and., Rudra A; Biocon-Bristol Myers Squibb Research and Development Center, Syngene International Ltd., Bangalore, India; and., Subramani S; Biocon-Bristol Myers Squibb Research and Development Center, Syngene International Ltd., Bangalore, India; and., Young J; Department of Discovery Biology, Bristol Myers Squibb, Princeton, NJ., Salter-Cid L; Department of Discovery Biology, Bristol Myers Squibb, Princeton, NJ., Malek TR; Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Coral Gables, FL., Struthers M; Department of Discovery Biology, Bristol Myers Squibb, Princeton, NJ; jenny.xie@bms.com Mary.Struthers@bms.com.
Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Jul 01; Vol. 207 (1), pp. 34-43. Date of Electronic Publication: 2021 Jun 09.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1550-6606
DOI:10.4049/jimmunol.2100078