PAI-1 induction during kidney injury promotes fibrotic epithelial dysfunction via deregulation of klotho, p53, and TGF-β1-receptor signaling.
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| Title: | PAI-1 induction during kidney injury promotes fibrotic epithelial dysfunction via deregulation of klotho, p53, and TGF-β1-receptor signaling. |
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| Authors: | Gifford CC; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA., Lian F; Division of Urology, Albany Medical College, Albany, NY, USA., Tang J; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA., Costello A; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA., Goldschmeding R; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., Samarakoon R; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA., Higgins PJ; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA.; Division of Urology, Albany Medical College, Albany, NY, USA. |
| Source: | FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Jul; Vol. 35 (7), pp. e21725. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1530-6860 |
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| DOI: | 10.1096/fj.202002652RR |
