PAI-1 induction during kidney injury promotes fibrotic epithelial dysfunction via deregulation of klotho, p53, and TGF-β1-receptor signaling.

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Title: PAI-1 induction during kidney injury promotes fibrotic epithelial dysfunction via deregulation of klotho, p53, and TGF-β1-receptor signaling.
Authors: Gifford CC; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA., Lian F; Division of Urology, Albany Medical College, Albany, NY, USA., Tang J; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA., Costello A; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA., Goldschmeding R; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., Samarakoon R; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA., Higgins PJ; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA.; Division of Urology, Albany Medical College, Albany, NY, USA.
Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Jul; Vol. 35 (7), pp. e21725.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PAI-1 induction during kidney injury promotes fibrotic epithelial dysfunction via deregulation of klotho, p53, and TGF-β1-receptor signaling.
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  Data: <searchLink fieldCode="AU" term="%22Gifford+CC%22">Gifford CC</searchLink>; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lian+F%22">Lian F</searchLink>; Division of Urology, Albany Medical College, Albany, NY, USA.<br /><searchLink fieldCode="AU" term="%22Tang+J%22">Tang J</searchLink>; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA.<br /><searchLink fieldCode="AU" term="%22Costello+A%22">Costello A</searchLink>; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA.<br /><searchLink fieldCode="AU" term="%22Goldschmeding+R%22">Goldschmeding R</searchLink>; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Samarakoon+R%22">Samarakoon R</searchLink>; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA.<br /><searchLink fieldCode="AU" term="%22Higgins+PJ%22">Higgins PJ</searchLink>; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, NY, USA.; Division of Urology, Albany Medical College, Albany, NY, USA.
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  Data: <searchLink fieldCode="JN" term="%228804484%22">FASEB journal : official publication of the Federation of American Societies for Experimental Biology</searchLink> [FASEB J] 2021 Jul; Vol. 35 (7), pp. e21725.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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        Value: 10.1096/fj.202002652RR
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      – TitleFull: PAI-1 induction during kidney injury promotes fibrotic epithelial dysfunction via deregulation of klotho, p53, and TGF-β1-receptor signaling.
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              Text: 2021 Jul
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