Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer.
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| Title: | Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer. |
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| Authors: | Freeman-Cook KD; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Hoffman RL; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Behenna DC; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Boras B; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Carelli J; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Diehl W; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Ferre RA; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., He YA; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Hui A; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Huang B; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Huser N; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Jones R; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Kephart SE; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Lapek J; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., McTigue M; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Miller N; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Murray BW; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Nagata A; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Nguyen L; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Niessen S; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Ninkovic S; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., O'Doherty I; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Ornelas MA; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Solowiej J; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Sutton SC; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Tran K; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Tseng E; Pfizer Global Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States., Visswanathan R; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Xu M; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Zehnder L; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Zhang Q; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Zhang C; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States., Dann S; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2021 Jul 08; Vol. 64 (13), pp. 9056-9077. Date of Electronic Publication: 2021 Jun 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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