Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes.

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Title: Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes.
Authors: Sjögren RJO; Department of Molecular Medicine and Surgery, Integrative Physiology, Karolinska Institutet, Stockholm, Sweden., Rizo-Roca D; Department of Molecular Medicine and Surgery, Integrative Physiology, Karolinska Institutet, Stockholm, Sweden., Chibalin AV; Department of Molecular Medicine and Surgery, Integrative Physiology, Karolinska Institutet, Stockholm, Sweden., Chorell E; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Furrer R; Biozentrum, University of Basel, Basel, Switzerland., Katayama S; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden., Harada J; Cardiovascular-Metabolics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan., Karlsson HKR; Department of Molecular Medicine and Surgery, Integrative Physiology, Karolinska Institutet, Stockholm, Sweden., Handschin C; Biozentrum, University of Basel, Basel, Switzerland., Moritz T; Swedish Metabolomics Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden., Krook A; Department of Physiology and Pharmacology, Integrative Physiology, Karolinska Institutet, Stockholm, Sweden., Näslund E; Division of Surgery, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden., Zierath JR; Department of Molecular Medicine and Surgery, Integrative Physiology, Karolinska Institutet, Stockholm, Sweden. juleen.zierath@ki.se.; Department of Physiology and Pharmacology, Integrative Physiology, Karolinska Institutet, Stockholm, Sweden. juleen.zierath@ki.se.
Source: Diabetologia [Diabetologia] 2021 Sep; Vol. 64 (9), pp. 2077-2091. Date of Electronic Publication: 2021 Jun 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0428
DOI:10.1007/s00125-021-05481-9