Intravitreal ranibizumab versus aflibercept versus bevacizumab for macular oedema due to central retinal vein occlusion: the LEAVO non-inferiority three-arm RCT.

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Title: Intravitreal ranibizumab versus aflibercept versus bevacizumab for macular oedema due to central retinal vein occlusion: the LEAVO non-inferiority three-arm RCT.
Authors: Hykin P; National Institute for Health Research Moorfields Biomedical Research Centre, London, UK.; Institute of Ophthalmology, University College London, London, UK., Prevost AT; Imperial Clinical Trials Unit, School of Public Health, Imperial College London, London, UK., Sivaprasad S; National Institute for Health Research Moorfields Biomedical Research Centre, London, UK.; Institute of Ophthalmology, University College London, London, UK., Vasconcelos JC; Imperial Clinical Trials Unit, School of Public Health, Imperial College London, London, UK., Murphy C; King's Clinical Trials Unit at King's Health Partners, King's College London, London, UK., Kelly J; King's Clinical Trials Unit at King's Health Partners, King's College London, London, UK., Ramu J; National Institute for Health Research Moorfields Biomedical Research Centre, London, UK., Alshreef A; School of Health and Related Research, University of Sheffield, Sheffield, UK., Flight L; School of Health and Related Research, University of Sheffield, Sheffield, UK., Pennington R; School of Health and Related Research, University of Sheffield, Sheffield, UK., Hounsome B, Lever E; King's Clinical Trials Unit at King's Health Partners, King's College London, London, UK., Metry A; School of Health and Related Research, University of Sheffield, Sheffield, UK., Poku E; School of Health and Related Research, University of Sheffield, Sheffield, UK., Yang Y; The Eye Infirmary, New Cross Hospital, Wolverhampton, UK., Harding SP; Eye and Vision Science, University of Liverpool, and St Paul's Eye Unit, Royal Liverpool University Hospitals, Liverpool, UK., Lotery A; Faculty of Medicine, University of Southampton, Southampton, UK., Chakravarthy U; Department of Biomedical Sciences, Queen's University Belfast, Belfast, UK., Brazier J; School of Health and Related Research, University of Sheffield, Sheffield, UK.
Source: Health technology assessment (Winchester, England) [Health Technol Assess] 2021 Jun; Vol. 25 (38), pp. 1-196.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Equivalence Trial
Journal Info: Publisher: NIHR Journals Library Country of Publication: England NLM ID: 9706284 Publication Model: Print Cited Medium: Internet ISSN: 2046-4924 (Electronic) Linking ISSN: 13665278 NLM ISO Abbreviation: Health Technol Assess Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2046-4924
DOI:10.3310/hta25380