Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11.1 activation in breast cancer cells and PDOs.
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| Title: | Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11.1 activation in breast cancer cells and PDOs. |
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| Authors: | Senyuk V; Division of Hematology Oncology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA., Eskandari N; Division of Hematology Oncology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA., Jiang Y; Division of Hematology Oncology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA; Departments of Anesthesiology and Pharmacology and Regenerative Medicine, University of Illinois, Chicago, IL, USA., Garcia-Varela R; Departments of Oncology and Medicine, Hematology and Oncology, and the UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA; Tecnologico de Monterrey, Centro de Biotecnologia-FEMSA, Escuela de Ingenieria y Ciencias, Monterrey N.L., Mexico., Sundstrom R; Departments of Oncology and Medicine, Hematology and Oncology, and the UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA., Leanza L; Department of Biology, University of Padova, Padova, Italy., Peruzzo R; Department of Biology, University of Padova, Padova, Italy., Burkard M; Departments of Oncology and Medicine, Hematology and Oncology, and the UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA., Minshall RD; Departments of Anesthesiology and Pharmacology and Regenerative Medicine, University of Illinois, Chicago, IL, USA., Gentile S; Division of Hematology Oncology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA. Electronic address: sgentile@uic.edu. |
| Source: | Redox biology [Redox Biol] 2021 Sep; Vol. 45, pp. 102030. Date of Electronic Publication: 2021 Jun 12. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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