FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS.

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Title: FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS.
Authors: Ferraro GB; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Ali A; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA., Luengo A; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Kodack DP; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Novartis Institutes for BioMedical Research, Cambridge, MA, USA., Deik A; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA., Abbott KL; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Bezwada D; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Blanc L; The Public Health Research Institute, New Jersey Medical School, Rutgers University, Newark, NJ, USA.; Institut de Chimie & Biologie des Membranes & des Nano-objets, CNRS UMR 5248, Bordeaux, France., Prideaux B; The Public Health Research Institute, New Jersey Medical School, Rutgers University, Newark, NJ, USA.; Department of Neuroscience, Cell Biology, and Anatomy, University of Texas Medical Branch, Galveston, TX, USA., Jin X; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA., Posada JM; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Chen J; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Chin CR; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Amoozgar Z; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Ferreira R; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden., Chen IX; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Naxerova K; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Ng C; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Westermark AM; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Duquette M; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Roberge S; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Lindeman NI; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Lyssiotis CA; Division of Signal Transduction, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.; University of Michigan, Ann Arbor, MI, USA., Nielsen J; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden., Housman DE; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Duda DG; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Brachtel E; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Golub TR; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA., Cantley LC; Division of Signal Transduction, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.; Weill Cornell Medicine and New York Presbyterian Hospital, New York, NY, USA., Asara JM; Division of Signal Transduction, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Davidson SM; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; Lewis Sigler Institute, Princeton University, Princeton, NJ, USA., Fukumura D; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Dartois VA; The Public Health Research Institute, New Jersey Medical School, Rutgers University, Newark, NJ, USA.; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Clish CB; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA., Jain RK; Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. jain@steele.mgh.harvard.edu., Vander Heiden MG; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. mvh@mit.edu.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA. mvh@mit.edu.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. mvh@mit.edu.; Dana-Farber Cancer Institute, Boston, MA, USA. mvh@mit.edu.
Source: Nature cancer [Nat Cancer] 2021 Apr; Vol. 2 (4), pp. 414-428. Date of Electronic Publication: 2021 Apr 01.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer
Database: MEDLINE Ultimate
Description
ISSN:2662-1347
DOI:10.1038/s43018-021-00183-y