Pharmacological and genetic manipulations at the µ-opioid receptor reveal arrestin-3 engagement limits analgesic tolerance and does not exacerbate respiratory depression in mice.
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| Title: | Pharmacological and genetic manipulations at the µ-opioid receptor reveal arrestin-3 engagement limits analgesic tolerance and does not exacerbate respiratory depression in mice. |
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| Authors: | He L; Center for Neuroscience, University of California-Davis, Davis, CA, USA.; Department of Physiology and Membrane Biology, UC Davis School of Medicine, Davis, CA, USA., Gooding SW; Center for Neuroscience, University of California-Davis, Davis, CA, USA., Lewis E; Center for Neuroscience, University of California-Davis, Davis, CA, USA., Felth LC; Center for Neuroscience, University of California-Davis, Davis, CA, USA., Gaur A; Center for Neuroscience, University of California-Davis, Davis, CA, USA., Whistler JL; Center for Neuroscience, University of California-Davis, Davis, CA, USA. jlwhistler@ucdavis.edu.; Department of Physiology and Membrane Biology, UC Davis School of Medicine, Davis, CA, USA. jlwhistler@ucdavis.edu. |
| Source: | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2021 Dec; Vol. 46 (13), pp. 2241-2249. Date of Electronic Publication: 2021 Jul 13. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8904907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-634X (Electronic) Linking ISSN: 0893133X NLM ISO Abbreviation: Neuropsychopharmacology Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1740-634X |
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| DOI: | 10.1038/s41386-021-01054-x |
