Gene-Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres.

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Title: Gene-Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres.
Authors: Modafferi S; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.; Department of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy., Zhong X; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Toxicology, School of Public Health, Sun Yat-sen University, Guangzhou, China., Kleensang A; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA., Murata Y; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.; Research Center, Nihon Nohyaku Co. Ltd., Osaka, Japan., Fagiani F; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.; Department of Drug Sciences, Pharmacology Section, University of Pavia, Pavia, Italy.; Istituto Universitario di Studi Superiori (Scuola Universitaria Superiore IUSS) Pavia, Pavia, Italy., Pamies D; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.; Department of Biomedical Science, University of Lausanne, Lausanne, Switzerland., Hogberg HT; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA., Calabrese V; Department of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy., Lachman H; Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, New York, USA.; Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, USA., Hartung T; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.; University of Konstanz, Konstanz, Germany., Smirnova L; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Source: Environmental health perspectives [Environ Health Perspect] 2021 Jul; Vol. 129 (7), pp. 77001. Date of Electronic Publication: 2021 Jul 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: National Institute of Environmental Health Sciences Country of Publication: United States NLM ID: 0330411 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-9924 (Electronic) Linking ISSN: 00916765 NLM ISO Abbreviation: Environ Health Perspect Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1552-9924
DOI:10.1289/EHP8580