A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site.
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| Title: | A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site. |
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| Authors: | Maehigashi T; Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia, United States of America., Ahn S; ST Pharm Co., Ltd., Seoul, South Korea., Kim UI; ST Pharm Co., Ltd., Seoul, South Korea., Lindenberger J; Division of Infectious Diseases, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Oo A; Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia, United States of America., Koneru PC; Division of Infectious Diseases, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Mahboubi B; Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia, United States of America., Engelman AN; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America., Kvaratskhelia M; Division of Infectious Diseases, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America., Kim K; ST Pharm Co., Ltd., Seoul, South Korea., Kim B; Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia, United States of America.; Center for Drug Discovery, Children's Healthcare of Atlanta, Atlanta, Georgia, United States of America. |
| Source: | PLoS pathogens [PLoS Pathog] 2021 Jul 22; Vol. 17 (7), pp. e1009671. Date of Electronic Publication: 2021 Jul 22 (Print Publication: 2021). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1553-7374 |
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| DOI: | 10.1371/journal.ppat.1009671 |
