Generation of a humanized FXII knock-in mouse-A powerful model system to test novel anti-thrombotic agents.

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Bibliographic Details
Title: Generation of a humanized FXII knock-in mouse-A powerful model system to test novel anti-thrombotic agents.
Authors: Beck S; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.; Rudolf Virchow Center, University of Würzburg, Würzburg, Germany., Stegner D; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.; Rudolf Virchow Center, University of Würzburg, Würzburg, Germany., Loroch S; Leibniz-Institut für Analytische Wissenschaften--ISAS, Dortmund, Germany., Baig AA; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.; Rudolf Virchow Center, University of Würzburg, Würzburg, Germany., Göb V; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany., Schumbrutzki C; Leibniz-Institut für Analytische Wissenschaften--ISAS, Dortmund, Germany., Eilers E; Leibniz-Institut für Analytische Wissenschaften--ISAS, Dortmund, Germany., Sickmann A; Leibniz-Institut für Analytische Wissenschaften--ISAS, Dortmund, Germany.; Medizinische Fakultät, Ruhr-Universität Bochum, Bochum, Germany.; College of Physical Sciences, University of Aberdeen, Old Aberdeen, UK., May F; CSL Behring GmbH, Marburg, Germany., Nolte MW; CSL Behring GmbH, Marburg, Germany., Panousis C; CSL Limited, Bio21 Institute, Parkville, Victoria, Australia., Nieswandt B; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.; Rudolf Virchow Center, University of Würzburg, Würzburg, Germany.
Source: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2021 Nov; Vol. 19 (11), pp. 2835-2840. Date of Electronic Publication: 2021 Aug 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1538-7836
DOI:10.1111/jth.15488