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Generation of a humanized FXII knock-in mouse-A powerful model system to test novel anti-thrombotic agents.

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Title: Generation of a humanized FXII knock-in mouse-A powerful model system to test novel anti-thrombotic agents.
Authors: Beck S; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.; Rudolf Virchow Center, University of Würzburg, Würzburg, Germany., Stegner D; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.; Rudolf Virchow Center, University of Würzburg, Würzburg, Germany., Loroch S; Leibniz-Institut für Analytische Wissenschaften--ISAS, Dortmund, Germany., Baig AA; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.; Rudolf Virchow Center, University of Würzburg, Würzburg, Germany., Göb V; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany., Schumbrutzki C; Leibniz-Institut für Analytische Wissenschaften--ISAS, Dortmund, Germany., Eilers E; Leibniz-Institut für Analytische Wissenschaften--ISAS, Dortmund, Germany., Sickmann A; Leibniz-Institut für Analytische Wissenschaften--ISAS, Dortmund, Germany.; Medizinische Fakultät, Ruhr-Universität Bochum, Bochum, Germany.; College of Physical Sciences, University of Aberdeen, Old Aberdeen, UK., May F; CSL Behring GmbH, Marburg, Germany., Nolte MW; CSL Behring GmbH, Marburg, Germany., Panousis C; CSL Limited, Bio21 Institute, Parkville, Victoria, Australia., Nieswandt B; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.; Rudolf Virchow Center, University of Würzburg, Würzburg, Germany.
Source: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2021 Nov; Vol. 19 (11), pp. 2835-2840. Date of Electronic Publication: 2021 Aug 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Generation of a humanized FXII knock-in mouse-A powerful model system to test novel anti-thrombotic agents.
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  Data: <searchLink fieldCode="AU" term="%22Beck+S%22">Beck S</searchLink>; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.; Rudolf Virchow Center, University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Stegner+D%22">Stegner D</searchLink>; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.; Rudolf Virchow Center, University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Loroch+S%22">Loroch S</searchLink>; Leibniz-Institut für Analytische Wissenschaften--ISAS, Dortmund, Germany.<br /><searchLink fieldCode="AU" term="%22Baig+AA%22">Baig AA</searchLink>; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.; Rudolf Virchow Center, University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Göb+V%22">Göb V</searchLink>; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schumbrutzki+C%22">Schumbrutzki C</searchLink>; Leibniz-Institut für Analytische Wissenschaften--ISAS, Dortmund, Germany.<br /><searchLink fieldCode="AU" term="%22Eilers+E%22">Eilers E</searchLink>; Leibniz-Institut für Analytische Wissenschaften--ISAS, Dortmund, Germany.<br /><searchLink fieldCode="AU" term="%22Sickmann+A%22">Sickmann A</searchLink>; Leibniz-Institut für Analytische Wissenschaften--ISAS, Dortmund, Germany.; Medizinische Fakultät, Ruhr-Universität Bochum, Bochum, Germany.; College of Physical Sciences, University of Aberdeen, Old Aberdeen, UK.<br /><searchLink fieldCode="AU" term="%22May+F%22">May F</searchLink>; CSL Behring GmbH, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Nolte+MW%22">Nolte MW</searchLink>; CSL Behring GmbH, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Panousis+C%22">Panousis C</searchLink>; CSL Limited, Bio21 Institute, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Nieswandt+B%22">Nieswandt B</searchLink>; Institute of Experimental Biomedicine I, University Hospital Würzburg, Würzburg, Germany.; Rudolf Virchow Center, University of Würzburg, Würzburg, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101170508%22">Journal of thrombosis and haemostasis : JTH</searchLink> [J Thromb Haemost] 2021 Nov; Vol. 19 (11), pp. 2835-2840. <i>Date of Electronic Publication: </i>2021 Aug 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101170508 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-7836 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215387836%22">15387836 </searchLink><i>NLM ISO Abbreviation: </i>J Thromb Haemost <i>Subsets: </i>MEDLINE
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        Value: 10.1111/jth.15488
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              Text: 2021 Nov
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