Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern.
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| Title: | Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern. |
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| Authors: | Skelly DT; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Nuffield Department of Clinial Neurosciences, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Harding AC; James and Lillian Martin Centre, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Gilbert-Jaramillo J; James and Lillian Martin Centre, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Knight ML; James and Lillian Martin Centre, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Longet S; Public Health England, Porton Down, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Brown A; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Adele S; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Adland E; Peter Medawar Building for Pathogen Research, Department of Paediatrics, University of Oxford, Oxford, UK., Brown H; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Tipton T; Public Health England, Porton Down, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Stafford L; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Mentzer AJ; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Johnson SA; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Medical Sciences Division, University of Oxford, Oxford, UK., Amini A; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Tan TK; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Schimanski L; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Centre for Translational Immunology, Chinese Academy of Medical Sciences, Oxford Institute, University of Oxford, Oxford, UK., Huang KA; Department of Infectious Diseases, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, and Taipei Medical University, Taipei, Taiwan., Rijal P; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Centre for Translational Immunology, Chinese Academy of Medical Sciences, Oxford Institute, University of Oxford, Oxford, UK., Frater J; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Goulder P; Peter Medawar Building for Pathogen Research, Department of Paediatrics, University of Oxford, Oxford, UK., Conlon CP; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Jeffery K; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Dold C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK., Pollard AJ; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK., Sigal A; Africa Health Research Institute, Durban, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, 4001, South Africa.; Max Planck Institute for Infection Biology, Berlin, Germany., de Oliveira T; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, 4001, South Africa.; KwaZulu-Natal Research Innovation and Sequencing Platform, Durban, South Africa.; Centre for the AIDS Programme of Research in South Africa, Durban, South Africa.; Department of Global Health, University of Washington, Seattle, WA, USA., Townsend AR; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Centre for Translational Immunology, Chinese Academy of Medical Sciences, Oxford Institute, University of Oxford, Oxford, UK., Klenerman P; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK., Dunachie SJ; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Barnes E; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK., Carroll MW; Public Health England, Porton Down, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., James WS; James and Lillian Martin Centre, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK. william.james@path.ox.ac.uk. |
| Corporate Authors: | Medawar Laboratory Team, OPTIC (Oxford Protective T cell Immunology for COVID-19) Clinical Group, PITCH (Protective Immunity T cells in Health Care Worker) Study Group, C-MORE/PHOSP-C Group |
| Source: | Nature communications [Nat Commun] 2021 Aug 17; Vol. 12 (1), pp. 5061. Date of Electronic Publication: 2021 Aug 17. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-021-25167-5 |
