Epigenetic inactivation of the autophagy-lysosomal system in appendix in Parkinson's disease.
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| Title: | Epigenetic inactivation of the autophagy-lysosomal system in appendix in Parkinson's disease. |
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| Authors: | Gordevicius J; Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI, USA. juozas.gordevicius@vai.org.; Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius, Lithuania. juozas.gordevicius@vai.org., Li P; Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI, USA., Marshall LL; Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI, USA., Killinger BA; Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI, USA.; Graduate College, Rush University Medical Center, Chicago, IL, USA., Lang S; Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI, USA., Ensink E; Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI, USA., Kuhn NC; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA., Cui W; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI, USA., Maroof N; Roche Pharma Research and Early Development, Neuroscience Discovery, Roche Innovation Center, Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland., Lauria R; Roche Pharma Research and Early Development, Neuroscience Discovery, Roche Innovation Center, Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland., Rueb C; Roche Pharma Research and Early Development, Neuroscience Discovery, Roche Innovation Center, Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland., Siebourg-Polster J; Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland., Maliver P; Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland., Lamp J; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA.; Integrated Mass Spectrometry Unit, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA., Vega I; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA.; Integrated Mass Spectrometry Unit, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA., Manfredsson FP; Department of Translational Neuroscience, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA.; Parkinson's Disease Research Unit, Department of Neurobiology, Barrow Neurological Institute, Phoenix, AZ, USA., Britschgi M; Roche Pharma Research and Early Development, Neuroscience Discovery, Roche Innovation Center, Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland., Labrie V; Center for Neurodegenerative Science, Van Andel Institute, Grand Rapids, MI, USA.; Division of Psychiatry and Behavioral Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA. |
| Source: | Nature communications [Nat Commun] 2021 Aug 26; Vol. 12 (1), pp. 5134. Date of Electronic Publication: 2021 Aug 26. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-021-25474-x |
