Physiologically Based Pharmacokinetic Modelling of Inhaled Nemiralisib: Mechanistic Components for Pulmonary Absorption, Systemic Distribution, and Oral Absorption.

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Title: Physiologically Based Pharmacokinetic Modelling of Inhaled Nemiralisib: Mechanistic Components for Pulmonary Absorption, Systemic Distribution, and Oral Absorption.
Authors: Miller NA; Simulations Plus, Inc., 42505 10th Street West, Lancaster, CA, 93534, USA. neil@simulations-plus.com., Graves RH; Simulations Plus, Inc., 42505 10th Street West, Lancaster, CA, 93534, USA., Edwards CD; GlaxoSmithKline R&D, Stevenage, Hertfordshire, UK., Amour A; GlaxoSmithKline R&D, Stevenage, Hertfordshire, UK., Taylor E; GlaxoSmithKline R&D, Gunnelswood Road, Ware, Hertfordshire, UK., Robb O; GlaxoSmithKline R&D, Stevenage, Hertfordshire, UK., O'Brien B; GlaxoSmithKline R&D, Stevenage, Hertfordshire, UK., Patel A; GlaxoSmithKline R&D, Gunnelswood Road, Ware, Hertfordshire, UK., Harrell AW; GlaxoSmithKline R&D, Gunnelswood Road, Ware, Hertfordshire, UK., Hessel EM; Eligo Bioscience, Paris, France.
Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2022 Feb; Vol. 61 (2), pp. 281-293. Date of Electronic Publication: 2021 Aug 30.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Adis, part of Springer Science+Business Media Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE
Database: MEDLINE Ultimate
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