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Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma.

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Title: Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma.
Authors: Nguyen TTT; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA., Shang E; Department of Biological Sciences, Bronx Community College, City University of New York, Bronx, New York, NY, USA., Shu C; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA., Kim S; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA., Mela A; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA., Humala N; Department of Neurological Surgery, Columbia University Medical Center, New York, NY, USA., Mahajan A; Department of Neurological Surgery, Columbia University Medical Center, New York, NY, USA., Yang HW; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA., Akman HO; Department of Neurology, Columbia University Medical Center, New York, NY, USA., Quinzii CM; Department of Neurology, Columbia University Medical Center, New York, NY, USA., Zhang G; Proteomics and Metabolomics Core Facility, Weill Cornell Medicine, New York, NY, USA., Westhoff MA; Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany., Karpel-Massler G; Department of Neurosurgery, Ulm University Medical Center, Ulm, Germany., Bruce JN; Department of Neurological Surgery, Columbia University Medical Center, New York, NY, USA., Canoll P; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA., Siegelin MD; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA. ms4169@cumc.columbia.edu.
Source: Nature communications [Nat Commun] 2021 Sep 01; Vol. 12 (1), pp. 5203. Date of Electronic Publication: 2021 Sep 01.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma.
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  Data: <searchLink fieldCode="AU" term="%22Nguyen+TTT%22">Nguyen TTT</searchLink>; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shang+E%22">Shang E</searchLink>; Department of Biological Sciences, Bronx Community College, City University of New York, Bronx, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shu+C%22">Shu C</searchLink>; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mela+A%22">Mela A</searchLink>; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Humala+N%22">Humala N</searchLink>; Department of Neurological Surgery, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mahajan+A%22">Mahajan A</searchLink>; Department of Neurological Surgery, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Yang+HW%22">Yang HW</searchLink>; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Akman+HO%22">Akman HO</searchLink>; Department of Neurology, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Quinzii+CM%22">Quinzii CM</searchLink>; Department of Neurology, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+G%22">Zhang G</searchLink>; Proteomics and Metabolomics Core Facility, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Westhoff+MA%22">Westhoff MA</searchLink>; Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Karpel-Massler+G%22">Karpel-Massler G</searchLink>; Department of Neurosurgery, Ulm University Medical Center, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Bruce+JN%22">Bruce JN</searchLink>; Department of Neurological Surgery, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Canoll+P%22">Canoll P</searchLink>; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Siegelin+MD%22">Siegelin MD</searchLink>; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA. ms4169@cumc.columbia.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2021 Sep 01; Vol. 12 (1), pp. 5203. <i>Date of Electronic Publication: </i>2021 Sep 01.
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