Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration.

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Title: Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration.
Authors: Ryan KC; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, New York, USA., Ashkavand Z; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, New York, USA., Sarasija S; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, New York, USA., Laboy JT; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, New York, USA., Samarakoon R; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, New York, USA., Norman KR; Department of Regenerative and Cancer Cell Biology, Albany Medical College, Albany, New York, USA.
Source: Aging cell [Aging Cell] 2021 Oct; Vol. 20 (10), pp. e13472. Date of Electronic Publication: 2021 Sep 09.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1474-9726
DOI:10.1111/acel.13472