View in EDS HTML Full Text PDF Full Text

Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.

Saved in:
Bibliographic Details
Title: Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.
Authors: Harshfield EL; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK. eh457@medschl.cam.ac.uk.; Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 0QQ, UK. eh457@medschl.cam.ac.uk., Fauman EB; Internal Medicine Research Unit, Pfizer Worldwide Research, Development and Medical, Cambridge, Massachusetts, 02139, USA., Stacey D; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Paul DS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, CB2 0QQ, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, CB2 0QQ, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Ziemek D; Inflammation and Immunology, Pfizer Worldwide Research, Development and Medical, 10785, Berlin, Germany., Ong RMY; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK., Danesh J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, CB2 0QQ, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, CB2 0QQ, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, CB2 0QQ, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, CB2 0QQ, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Rasheed A; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Sattar T; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Zameer-Ul-Asar; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Saleem I; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Hina Z; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Ishtiaq U; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Qamar N; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan., Mallick NH; Punjab Institute of Cardiology, Lahore, 42000, Pakistan., Yaqub Z; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan., Saghir T; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan., Rizvi SNH; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan., Memon A; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan., Ishaq M; Karachi Institute of Heart Diseases, Karachi, 75950, Pakistan., Rasheed SZ; Karachi Institute of Heart Diseases, Karachi, 75950, Pakistan., Memon FU; Red Crescent Institute of Cardiology, Hyderabad, 71500, Pakistan., Jalal A; Faisalabad Institute of Cardiology, Faisalabad, 38000, Pakistan., Abbas S; Faisalabad Institute of Cardiology, Faisalabad, 38000, Pakistan., Frossard P; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan., Saleheen D; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan.; Department of Biostatistics & Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA., Wood AM; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, CB2 0QQ, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, CB2 0QQ, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK., Griffin JL; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, CB2 1GA, UK. julian.griffin@imperial.ac.uk.; Section of Biomolecular Medicine, Division of Systems Medicine, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, SW7 2AZ, UK. julian.griffin@imperial.ac.uk., Koulman A; Core Metabolomics and Lipidomics Laboratory, National Institute for Health Research, Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, UK. ak675@medschl.cam.ac.uk.
Source: BMC medicine [BMC Med] 2021 Sep 10; Vol. 19 (1), pp. 232. Date of Electronic Publication: 2021 Sep 10.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190723 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7015 (Electronic) Linking ISSN: 17417015 NLM ISO Abbreviation: BMC Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 34503513
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Harshfield+EL%22">Harshfield EL</searchLink>; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK. eh457@medschl.cam.ac.uk.; Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 0QQ, UK. eh457@medschl.cam.ac.uk.<br /><searchLink fieldCode="AU" term="%22Fauman+EB%22">Fauman EB</searchLink>; Internal Medicine Research Unit, Pfizer Worldwide Research, Development and Medical, Cambridge, Massachusetts, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Stacey+D%22">Stacey D</searchLink>; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.<br /><searchLink fieldCode="AU" term="%22Paul+DS%22">Paul DS</searchLink>; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, CB2 0QQ, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, CB2 0QQ, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Ziemek+D%22">Ziemek D</searchLink>; Inflammation and Immunology, Pfizer Worldwide Research, Development and Medical, 10785, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Ong+RMY%22">Ong RMY</searchLink>; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.<br /><searchLink fieldCode="AU" term="%22Danesh+J%22">Danesh J</searchLink>; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, CB2 0QQ, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, CB2 0QQ, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Butterworth+AS%22">Butterworth AS</searchLink>; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, CB2 0QQ, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, CB2 0QQ, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Rasheed+A%22">Rasheed A</searchLink>; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan.<br /><searchLink fieldCode="AU" term="%22Sattar+T%22">Sattar T</searchLink>; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan.<br /><searchLink fieldCode="AU" term="%22Zameer-Ul-Asar%22">Zameer-Ul-Asar</searchLink>; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan.<br /><searchLink fieldCode="AU" term="%22Saleem+I%22">Saleem I</searchLink>; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan.<br /><searchLink fieldCode="AU" term="%22Hina+Z%22">Hina Z</searchLink>; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan.<br /><searchLink fieldCode="AU" term="%22Ishtiaq+U%22">Ishtiaq U</searchLink>; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan.<br /><searchLink fieldCode="AU" term="%22Qamar+N%22">Qamar N</searchLink>; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan.<br /><searchLink fieldCode="AU" term="%22Mallick+NH%22">Mallick NH</searchLink>; Punjab Institute of Cardiology, Lahore, 42000, Pakistan.<br /><searchLink fieldCode="AU" term="%22Yaqub+Z%22">Yaqub Z</searchLink>; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan.<br /><searchLink fieldCode="AU" term="%22Saghir+T%22">Saghir T</searchLink>; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan.<br /><searchLink fieldCode="AU" term="%22Rizvi+SNH%22">Rizvi SNH</searchLink>; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan.<br /><searchLink fieldCode="AU" term="%22Memon+A%22">Memon A</searchLink>; National Institute of Cardiovascular Diseases, Karachi, 75510, Pakistan.<br /><searchLink fieldCode="AU" term="%22Ishaq+M%22">Ishaq M</searchLink>; Karachi Institute of Heart Diseases, Karachi, 75950, Pakistan.<br /><searchLink fieldCode="AU" term="%22Rasheed+SZ%22">Rasheed SZ</searchLink>; Karachi Institute of Heart Diseases, Karachi, 75950, Pakistan.<br /><searchLink fieldCode="AU" term="%22Memon+FU%22">Memon FU</searchLink>; Red Crescent Institute of Cardiology, Hyderabad, 71500, Pakistan.<br /><searchLink fieldCode="AU" term="%22Jalal+A%22">Jalal A</searchLink>; Faisalabad Institute of Cardiology, Faisalabad, 38000, Pakistan.<br /><searchLink fieldCode="AU" term="%22Abbas+S%22">Abbas S</searchLink>; Faisalabad Institute of Cardiology, Faisalabad, 38000, Pakistan.<br /><searchLink fieldCode="AU" term="%22Frossard+P%22">Frossard P</searchLink>; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan.<br /><searchLink fieldCode="AU" term="%22Saleheen+D%22">Saleheen D</searchLink>; Center for Non-Communicable Diseases, Karachi, 75300, Pakistan.; Department of Biostatistics & Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Wood+AM%22">Wood AM</searchLink>; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, CB2 0QQ, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, CB2 0QQ, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Griffin+JL%22">Griffin JL</searchLink>; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, CB2 1GA, UK. julian.griffin@imperial.ac.uk.; Section of Biomolecular Medicine, Division of Systems Medicine, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, SW7 2AZ, UK. julian.griffin@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Koulman+A%22">Koulman A</searchLink>; Core Metabolomics and Lipidomics Laboratory, National Institute for Health Research, Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, UK. ak675@medschl.cam.ac.uk.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101190723%22">BMC medicine</searchLink> [BMC Med] 2021 Sep 10; Vol. 19 (1), pp. 232. <i>Date of Electronic Publication: </i>2021 Sep 10.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190723 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1741-7015 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217417015%22">17417015 </searchLink><i>NLM ISO Abbreviation: </i>BMC Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=34503513
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1186/s12916-021-02087-1
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 232
    Titles:
      – TitleFull: Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Harshfield EL
      – PersonEntity:
          Name:
            NameFull: Fauman EB
      – PersonEntity:
          Name:
            NameFull: Stacey D
      – PersonEntity:
          Name:
            NameFull: Paul DS
      – PersonEntity:
          Name:
            NameFull: Ziemek D
      – PersonEntity:
          Name:
            NameFull: Ong RMY
      – PersonEntity:
          Name:
            NameFull: Danesh J
      – PersonEntity:
          Name:
            NameFull: Butterworth AS
      – PersonEntity:
          Name:
            NameFull: Rasheed A
      – PersonEntity:
          Name:
            NameFull: Sattar T
      – PersonEntity:
          Name:
            NameFull: Zameer-Ul-Asar
      – PersonEntity:
          Name:
            NameFull: Saleem I
      – PersonEntity:
          Name:
            NameFull: Hina Z
      – PersonEntity:
          Name:
            NameFull: Ishtiaq U
      – PersonEntity:
          Name:
            NameFull: Qamar N
      – PersonEntity:
          Name:
            NameFull: Mallick NH
      – PersonEntity:
          Name:
            NameFull: Yaqub Z
      – PersonEntity:
          Name:
            NameFull: Saghir T
      – PersonEntity:
          Name:
            NameFull: Rizvi SNH
      – PersonEntity:
          Name:
            NameFull: Memon A
      – PersonEntity:
          Name:
            NameFull: Ishaq M
      – PersonEntity:
          Name:
            NameFull: Rasheed SZ
      – PersonEntity:
          Name:
            NameFull: Memon FU
      – PersonEntity:
          Name:
            NameFull: Jalal A
      – PersonEntity:
          Name:
            NameFull: Abbas S
      – PersonEntity:
          Name:
            NameFull: Frossard P
      – PersonEntity:
          Name:
            NameFull: Saleheen D
      – PersonEntity:
          Name:
            NameFull: Wood AM
      – PersonEntity:
          Name:
            NameFull: Griffin JL
      – PersonEntity:
          Name:
            NameFull: Koulman A
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 10
              M: 09
              Text: 2021 Sep 10
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-electronic
              Value: 1741-7015
          Numbering:
            – Type: volume
              Value: 19
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: BMC medicine
              Type: main
ResultId 1