Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer.

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Title: Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer.
Authors: Shah VV; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Duncan AD; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Epigenetics and Molecular Carcinogenesis, Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, University of Texas, Houston, TX, USA.; Salarius Pharmaceuticals, Houston, TX, USA., Jiang S; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Thoracic Head and Neck Medicine Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Stratton SA; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Epigenetics and Molecular Carcinogenesis, Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Allton KL; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; The Neurodegeneration Consortium, Therapeutics Discovery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Yam C; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Jain A; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Epigenetics and Molecular Carcinogenesis, Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, University of Texas, Houston, TX, USA., Krause PM; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lu Y; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Epigenetics and Molecular Carcinogenesis, Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Cai S; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Tu Y; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhou X; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhang X; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Jiang Y; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Carroll CL; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Institute of Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kang Z; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Institute of Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Liu B; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Epigenetics and Molecular Carcinogenesis, Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Shen J; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Epigenetics and Molecular Carcinogenesis, Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Gagea M; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Manu SM; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Epigenetics and Molecular Carcinogenesis, Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Huo L; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Gilcrease M; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Powell RT; Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M College of Medicine, Houston, TX, USA., Guo L; Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M College of Medicine, Houston, TX, USA., Stephan C; Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M College of Medicine, Houston, TX, USA., Davies PJ; Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M College of Medicine, Houston, TX, USA., Parker-Thornburg J; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lozano G; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, University of Texas, Houston, TX, USA., Behringer RR; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, University of Texas, Houston, TX, USA., Piwnica-Worms H; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, University of Texas, Houston, TX, USA.; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Chang JT; University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, University of Texas, Houston, TX, USA. jeffrey.t.chang@uth.tmc.edu.; Department of Integrative Biology and Pharmacology, University of Texas Health Sciences Center at Houston, Houston, TX, USA. jeffrey.t.chang@uth.tmc.edu., Moulder SL; The University of Texas MD Anderson Cancer Center, Houston, TX, USA. smoulder@mdanderson.org.; Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. smoulder@mdanderson.org., Barton MC; The University of Texas MD Anderson Cancer Center, Houston, TX, USA. bartonsh@ohsu.edu.; Department of Epigenetics and Molecular Carcinogenesis, Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. bartonsh@ohsu.edu.; University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, University of Texas, Houston, TX, USA. bartonsh@ohsu.edu.; Division of Oncological Sciences, Cancer Early Detection Advanced Research, Center Knight Cancer Institute Oregon Health & Science University, Portland, OR, USA. bartonsh@ohsu.edu.
Source: Nature communications [Nat Commun] 2021 Sep 10; Vol. 12 (1), pp. 5389. Date of Electronic Publication: 2021 Sep 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-021-25650-z