Encephalopathy-causing mutations in Gβ1 (GNB1) alter regulation of neuronal GIRK channels.

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Title: Encephalopathy-causing mutations in Gβ1 (GNB1) alter regulation of neuronal GIRK channels.
Authors: Reddy HP; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India., Yakubovich D; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Department of Pediatrics, Schneider Children's Medical Center, Petah Tikva, Israel., Keren-Raifman T; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Tabak G; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Tsemakhovich VA; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Pedersen MH; Departments of Psychiatry & Molecular Pharmacology and Therapeutics, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, København, Denmark., Shalomov B; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Colombo S; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY10032, USA., Goldstein DB; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY10032, USA.; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY10032, USA., Javitch JA; Departments of Psychiatry & Molecular Pharmacology and Therapeutics, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA., Bera AK; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India., Dascal N; Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, 6997801, Israel.
Source: IScience [iScience] 2021 Aug 21; Vol. 24 (9), pp. 103018. Date of Electronic Publication: 2021 Aug 21 (Print Publication: 2021).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2589-0042
DOI:10.1016/j.isci.2021.103018